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醫療團隊

專業的醫護人員，提供最佳的醫療服務

醫師介紹

  •

李宗海醫師

腦血管疾病
  • 國語,英語,閩南語,日語
  • 教授
醫師網路掛號
直接點選進入醫師網路掛號畫面
醫師資歷
  • 現職
    • 林口長庚紀念醫院教授級主治醫師
  • 學歷
    • 高雄醫學院醫學系學士
    • 日本東北大學神經內科學醫學博士
  • 經歷
    • 台灣腦中風學會理事長
    • 林口長庚紀念醫院腦血管科主任
    • 林口長庚紀念醫院腦中風中心主任
    • 林口長庚紀念醫院神經內科主治醫師
    • 林口長庚紀念醫院神經內科住院醫師
  • 學會與認證
    • 台灣神經學學會
    • 台灣腦中風學會
    • 中華民國醫用超音波學會
    • 神經科專科醫師證書
    • 神經重症專科醫師證書
  • 論文及期刊發表
    • A Brain-Protective Sterol from Soft Coral Inhibits Lipopolysaccharide-Induced Matrix Metalloproteinase-9-Mediated Astrocytic Migration.
      Biomedicines. 2024 Jan 19;12(1):226. doi: 10.3390/biomedicines12010226.
      Tsong-Hai Lee, Jiun-Liang Chen, Chuan-Hsin Chang, Ming-Ming Tsai, Hui-Ching Tseng, Yu-Chia Chang, Velayuthaprabhu Shanmugam, Hsi-Lung Hsieh*.
    • Localization of early infarction on non-contrast CT images in acute ischemic stroke with deep learning approach.
      Sci Rep. 2023 Nov 9;13(1):19442. doi: 10.1038/s41598-023-45573-7.
      Sulagna Mohapatra, Tsong-Hai Lee, Prasan Kumar Sahoo*, Ching-Yi Wu.
    • Early Antiplatelet Resumption and the Risks of Major Bleeding After Intracerebral Hemorrhage.
      Stroke. 2023 Feb;54(2):537-545. doi: 10.1161/STROKEAHA.122.040500. Epub 2023 Jan 9.
      Chi-Hung Liu, Yi-Ling Wu, Chih-Cheng Hsu*, Tsong-Hai Lee*.
    • Automatic identification of early ischemic lesions on non?contrast CT with deep learning approach.
      Sci Rep. 2022 Oct 27;12(1):18054. doi: 10.1038/s41598-022-22939-x.
      Prasan Kumar Sahoo, Sulagna Mohapatra, Ching-Yi Wu, Kuo-Lun Huang, Ting-Yu Chang, Tsong-Hai Lee*.
    • Identification of Metabolomics Biomarkers in Extracranial Carotid Artery Stenosis.
      Cells. 2022 Sep 27;11(19):3022. doi: 10.3390/cells11193022.
      Chia-Ni Lin, Kai-Cheng Hsu, Kuo-Lun Huang, Wen-Cheng Huang, Yi-Lun Hung, Tsong-Hai Lee*.
    • Mediating roles of leukoaraiosis and infarcts in the effects of unilateral carotid artery stenosis on cognition.
      Front Aging Neurosci. 2022 Sep 29:14:972480. doi: 10.3389/fnagi.2022.972480. eCollection 2022.
      Kuo-Lun Huang, Ting-Yu Chang, Yi-Ming Wu, Yeu-Jhy Chang, Hsiu-Chuan Wu, Chi-Hung Liu, Tsong-Hai Lee*, Meng-Yang Ho*.
    • Brain Protective Effect of Resveratrol via Ameliorating Interleukin-1-Induced MMP-9-Mediated Disruption of ZO-1 Arranged Integrity.
      Biomedicines. 2022 May 29;10(6):1270. doi: 10.3390/biomedicines10061270.
      Ming-Ming Tsai, Jiun-Liang Chen, Tsong-Hai Lee, Hsiuming Liu, Velayuthaprabhu Shanmugam, Hsi-Lung Hsieh*.
    • Cognitive Sequelae of Silent Ischemic Lesions Following Carotid Artery Stenting: Possible Role of Age-Related Moderation.
      Front Aging Neurosci. 2022 Jan 12:13:732617. doi: 10.3389/fnagi.2021.732617. eCollection 2021.
      Kuo-Lun Huang, Meng-Yang Ho, Yeu-Jhy Chang, Chien-Hung Chang, Chi-Hung Liu, Hsiu-Chuan Wu, Ting-Yu Chang*, Tsong-Hai Lee*.
    • Neurodegeneration and Vascular Burden on Cognition After Midlife: A Plasma and Neuroimaging Biomarker Study.
      Front Hum Neurosci. 2021 Dec 14:15:735063. doi: 10.3389/fnhum.2021.735063. eCollection 2021.
      Kuo-Lun Huang, Ing-Tsung Hsiao, Ting-Yu Chang, Shieh-Yueh Yang, Yeu-Jhy Chang, Hsiu-Chuan Wu, Chi-Hung Liu , Yi-Ming Wu, Kun-Ju Lin, Meng-Yang Ho*, Tsong-Hai Lee*.
    • Initial in-hospital heart rate is associated with long-term survival in patients with acute ischemic stroke.
      Clin Res Cardiol. 2022 Jun;111(6):651-662. doi: 10.1007/s00392-021-01953-5. Epub 2021 Oct 23.
      Jiann-Der Lee, Ya-Wen Kuo, Chuan-Pin Lee, Yen-Chu Huang, Meng Lee, Tsong-Hai Lee*.
    • Induced pluripotent stem cells can improve thrombolytic effect of low?dose rt-PA after acute carotid thrombosis in rat.
      Stem Cell Res Ther. 2021 Oct 21;12(1):549. doi: 10.1186/s13287-021-02615-z.
      Hsi-Lung Hsieh, Ching-Chung Liang, Cheng-You Lu, Jen-Tsung Yang, Chiu-Yen Chung, Yu-Shien Ko, Tsong-Hai Lee*.
    • Total plaque score helps to determine follow-up strategy for carotid artery stenosis progression in head and neck cancer patients after radiation therapy.
      PLoS One. 2021 Feb 12;16(2):e0246684. doi: 10.1371/journal.pone.0246684. eCollection 2021.
      Chi-Hung Liu, Joseph Tung-Chieh Chang, Tsong-Hai Lee, Pi-Yueh Chang, Chien-Hung Chang, Hsiu-Chuan Wu, Ting-Yu Chang, Kuo-Lun Huang, Chien-Yu Lin, Kang-Hsing Fan, Chan-Lin Chu, Yeu-Jhy Chang*.
    • Hypothyroidism and risks of cerebrovascular complications among patients with head and neck cancer after radiotherapy.
      BMC Neurol. 2021 Jan 19;21(1):30. doi: 10.1186/s12883-021-02047-5.
      Chi-Hung Liu, Joseph Tung-Chieh Chang, Tsong-Hai Lee, Pi-Yueh Chang, Chien-Hung Chang, Hsiu-Chuan Wu, Ting-Yu Chang, Kuo-Lun Huang, Chien-Yu Lin, Kang-Hsing Fan, Yeu-Jhy Chang*.
    • Protective effects of ischemic preconditioning against neuronal apoptosis and dendritic injury in the hippocampus are age-dependent.
      Journal of Neurochemistry. 2020 Nov; 155(4): 430-447. doi: 10.1111/jnc.15029. Epub 2020 Jun 15.
      Tsong-Hai Lee, Jen-Tsung Yang, Jr-Rung Lin, Chaur-Jong Hu, Wen-Hai Chou, Ching-Po Lin, Nai-Fang Chi*.
    • The COX-2-derived PGE 2 autocrine contributes to bradykinin-induced matrix metalloproteinase-9 expression and astrocytic migration via STAT3 signaling.
      Cell Commun Signal. 2020 Nov 23;18(1):185. doi: 10.1186/s12964-020-00680-0.
      Tsong-Hai Lee, Pei-Shan Liu, Ming-Ming Tsai, Jiun-Liang Chen, Su-Jane Wang, Hsi-Lung Hsieh*.
    • Impact of chronic kidney disease severity on causes of death after first-ever stroke: A population-based study using nationwide data linkage.
      PLoS One. 2020 Nov 19;15(11):e0241891. doi: 10.1371/journal.pone.0241891. eCollection 2020.
      Hsin-Hsu Wu*, Ting-Yu Chang, Chi-Hung Liu, Jr-Rung Lin, Chia-Wei Liou, Jiann-Der Lee, Tsung-I Peng, Meng Lee, Tsong-Hai Lee.
    • Investigation of reactive astrogliosis effect on post-stroke cognitive impairment.
      J Neuroinflammation. 2020 Oct 17;17(1):308. doi: 10.1186/s12974-020-01985-0.
      Kuo-Lun Huang, Ing-Tsung Hsiao, Meng-Yang Ho, Jung-Lung Hsu, Yeu-Jhy Chang, Ting-Yu Chang, Chi-Hung Liu, Chien-Hung Chang, Yi-Ming Wu, Kuan-Yi Wu, Shiaw-Pyng Wey, Tzu-Chen Yen, Nobuyuki Okamura, Tsong-Hai Lee*, Kun-Ju Lin*.
    • Maintenance of Stroke Care Quality amid the Coronavirus Disease 2019 Outbreak in Taiwan.
      J Stroke. 2020 Sep;22(3):407-411. doi: 10.5853/jos.2020.02292. Epub 2020 Sep 29.
      Chih-Hao Chen, Chi-Hung Liu, Nai-Fang Chi, Pi-Shan Sung, Cheng-Yang Hsieh, Meng Lee, Sung-Chun Tang, Jiann-Shing Jeng, Taiwan Stroke Society Investigators.
    • Comparison of long-term efficacy and safety between cilostazol and clopidogrel in chronic ischemic stroke: a nationwide cohort study.
      Ther Adv Chronic Dis. 2020 Jul 30;11:2040622320936418. doi: 10.1177/2040622320936418. eCollection 2020.
      Tsong-Hai Lee, Yu-Sheng Lin, Chia-Wei Liou, Jiann-Der Lee, Tsung-I Peng, Chi-Hung Liu*.
    • J Neuroinflammation. 2020 Jun 6;17(1):177. doi: 10.1186/s12974-020-01859-5.
      Rottlerin, a natural polyphenol compound, inhibits upregulation of matrix metalloproteinase-9 and brain astrocytic migration by reducing PKC-δ-dependent ROS signal.
      Tsong-Hai Lee, Jiun-Liang Chen, Pei-Shan Liu, Ming-Ming Tsai, Su-Jane Wang, Hsi-Lung Hsieh*.
    • Computed Tomography Angiography in Acute Stroke Patients Receiving Recombinant Tissue Plasminogen Activator: Outcome and Safety Evaluations in an Asian Population.
      Cerebrovasc Dis. 2020 Feb 5:1-8. doi: 10.1159/000504776. [Epub ahead of print]
      Lin CM, Wu HC, Wu YM, Liu CH, Chang KH, Chang TY, Huang KL, Chang YJ, Lee TH, Tsay PK, Cheng CK, Chang CH*.
    • Pioglitazone and PPAR-γ modulating treatment in hypertensive and type 2 diabetic patients after ischemic stroke: a national cohort study.
      Cardiovasc Diabetol. 2020 Jan 7;19(1):2. doi: 10.1186/s12933-019-0979-x.
      Liu CH, Lee TH, Lin YS, Sung PS, Wei YC, Li YR*.
    • Brain computerized tomography reading in suspected acute ischemic stroke patients: what are essentials for medical students?
      BMC Med Educ. 2019 Sep 18;19(1):359. doi: 10.1186/s12909-019-1781-x.
      Liu CH, Hsiao CT, Chang TY, Chang YJ*, Kuo SH, Chang CW, Chen CJ, Chen CF, Cheng PL, Chin SC, Chiu TF, Hsu JL1, Hsu PW, Lee TH, Liao CH, Lin CJ, Lin LH, Seak CJ, Sung PS, Yang TC, Wu YM.
    • Metabolomics study in severe extracranial carotid artery stenosis.
      BMC Neurol. 2019 Jun 24;19(1):138. doi: 10.1186/s12883-019-1371-x.
      Lee TH, Cheng ML, Shiao MS, Lin CN*.
    • Genomic screening of Fabry disease in young stroke patients: the Taiwan experience and a review of the literature.
      Eur J Neurol. 2019 Mar;26(3):553-555. doi: 10.1111/ene.13775. Epub 2018 Sep 9.
      Lee TH*, Yang JT, Lee JD, Chang KC, Peng TI, Chang TY, Huang KL, Liu CH, Ryu SJ, Burlina AP.
    • Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke Patients Receiving Thrombectomy: Standard or Low Dose Therapy?
      Curr Neurovasc Res. 2018;15(3):204-210. doi: 10.2174/1567202615666180717113526.
      Lin CH, Liu CH, Wang AY, Wu YM, Chen CC, Tsai YH, Chang TY, Huang KL, Wu HC, Lee TH, Chang YJ, Lin CM, Cheng CK, Chang CH*.
    • Choices for long-term hypertensive control in patients after first-ever hemorrhagic stroke: a nationwide cohort study.
      Ther Adv Neurol Disord. 2018 Sep 28;11:1756286418802688. doi: 10.1177/1756286418802688. eCollection 2018.
      Liu CH, Lin YS, Chi CC, Liou CW, Lee JD, Peng TI, Lee TH*.
    • Lipid Paradox in Statin-Naive Acute Ischemic Stroke But Not Hemorrhagic Stroke.
      Front Neurol. 2018 Aug 29;9:541. doi: 10.3389/fneur.2018.00541. eCollection 2018.
      Cheng KH, Lin JR, Anderson CS, Lai WT, Lee TH*; SRICHS Group.
    • The correlation of asymmetrical functional connectivity with cognition and reperfusion in carotid stenosis patients.
      Neuroimage Clin. 2018 Aug 9;20:476-484. doi: 10.1016/j.nicl.2018.08.011. eCollection 2018.
      Huang KL, Chang TY, Ho MY, Chen WH, Yeh MY, Chang YJ, Wong HF, Chang CH, Liu CH, Lee TH*, Wu CW*.
    • Causes of Death in Different Subtypes of Ischemic and Hemorrhagic Stroke.
      Angiology. 2018 Aug;69(7):582-590. doi: 10.1177/0003319717738687. Epub 2017 Nov 5.
      Liu CH, Lin JR, Liou CW, Lee JD, Peng TI, Lee M, Lee TH*; SRICHS Group.
    • Visualization of ischemic stroke-related changes on 18F-THK-5351 positron emission tomography.
      EJNMMI Res. 2018 Jul 16;8(1):62. doi: 10.1186/s13550-018-0417-1.
      Huang KL, Hsu JL, Lin KJ, Chang CH, Wu YM, Chang TY, Chang YJ, Liu CH, Ho MY, Wey SP, Yen TC, Okamura N, Hsiao IT, Lee TH*.
    • Changes in E-Selectin Levels Predict Carotid Stenosis Progression after Carotid Artery Stenting.
      Curr Neurovasc Res. 2018 Mar 19. doi: 10.2174/1567202615666180319150021. [Epub ahead of print]
      Liu CH, Lee TH, Chang PY, Chang CH, Wu HC, Chang TY, Huang KL, Cheng CK, Chang YJ*.
    • A genome-wide association study links small-vessel ischemic stroke to autophagy.
      Sci Rep. 2017 Nov 9;7(1):15229. doi: 10.1038/s41598-017-14355-3.
      Lee TH, Ko TM, Chen CH, Chang YJ, Lu LS, Chang CH, Huang KL, Chang TY, Lee JD, Chang KC, Yang JT, Wen MS, Wang CY, Chen YT, Chen TC, Chou SY, Lee MM, Chen YT*, Wu JY*.
    • Asymmetric Cerebrovascular Collateral Supply Affects Cognition in Patients with Unilateral Carotid Artery Stenosis.Asymmetric Cerebrovascular Collateral Supply Affects Cognition in Patients with Unilateral Carotid Artery Stenosis.
      Curr Neurovasc Res. 2017;14(4):347-358. doi: 10.2174/1567202614666171005141716.
      Huang KL, Chang TY, Chang CH, Liu HL, Chang YJ, Liu CH, Wong HF, Wu YM, Lee TH*, Ho MY*.
    • Early-phase 18F-AV-45 PET Imaging can Detect Crossed Cerebellar Diaschisis Following Carotid Artery Stenosis and Cerebral Hypoperfusion.
      Curr Neurovasc Res. 2017;14(3):258-265.
      Lee TH, Huang KL, Chang TY, Ho MY, Wey SP, Hsieh CJ, Yen TC, Lin KJ, Hsiao IT.
    • Improved thrombolytic effect with focused ultrasound and neuroprotective agent against acute carotid artery thrombosis in rat.
      Sci Rep. 2017 ;7(1):1638.
      Lee TH, Yeh JC, Tsai CH, Yang JT, Lou SL, Seak CJ, Wang CY, Wei KC, Liu HL.
    • To Load or Not to Load? Aspirin Loading in Acute Ischemic Stroke: A Study of ClinicalOutcomes.
      J Stroke Cerebrovasc Dis. 2016 ;25(10):2439-47.
      Su TH, Chan YL, Lee JD, Lee M, Lin LC, Wen YW,* Lee TH.
    • The Protective Effect of Human Umbilical Cord Blood CD34+ Cells and Estradiol against Focal Cerebral Ischemia in Female Ovariectomized Rat: Cerebral MR Imaging and Immunohistochemical Study.
      PLoS One 2016; 11(1):e0147133.
      Liang CC, Liu HL, Chang SD, Chen SH, *Lee TH.
    • Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study.
      J Am Heart Assoc. 2016; 4(3):e003003.
      Lee TH, Ko TM, Chen CH, Lee MT, Chang YJ, Chang CH, Huang KL, Chang TY, Lee JD, Chang KC, Yang JT, Wen MS, Wang CY, Chen YT, Hsieh CS, Chou SY, Liu YM, Chen HW, Liao HT, Wang CW, Chen SP, Lu LS, Chen YT, *Wu JY.
    • InvestigatorsInitial blood pressure is associated with stroke severity and is predictive of admission cost and one-year outcome in different stroke subtypes: a SRICHS registry study.
      BMC Neurology 2016; 16:27.
      Liu CH, Wei YC, Lin JR, Chang CH, Chang TY, Huang KL, Chang YJ, Ryu SJ, Lin LC, *Lee TH.
    • Graph Theoretical Analysis of Functional Networks and Its Relationship to Cognitive Decline in Patients with Carotid Stenosis.
      J Cereb Blood Flow Metab. 2016;36(4):808-18.
      Chang TY, Huang KL, Ho MY, Ho PS, Chang CH, Liu CH, Chang YJ, Wong HF, Hsieh IC, *Lee TH, Liu HL.
    • Evaluation of Anti-Infammatory Effects of Helminthostachys zeylanica Extracts viaInhibiting Bradykinin-Induced MMP-9 Expression in Brain Astrocytes.
      Mol Neurobiol. 2016; 53(9):5995-6005.
      Hsieh HL, Yang SH, Lee TH, Fang JY, Lin CF.
    • Timing of Symptomatic Infarct Swelling Following Intravenous Thrombolysis in AcuteMiddle Cerebral Artery Infarction: A Case-Control Study.
      Clin Appl Thromb Hemost. 2016; 21. pii: 1076029616659693. [Epub ahead of print]
      Lin TC, Lee JD, Lin YH, Yuan RY, Weng HH, Huang YC, Lee M, Wu CY, Hsu HL, Hsu CY, Lee TH, Liu SJ, Chang YJ, Chang CH, Peng TI, Liou CW, Chang KC, Pan YT, Huang YC.
    • Effect of dehydration on the development of collaterals in acute middle cerebral arteryocclusion .
      Eur J Neurol. 2016 ;23(3):494-500.
      Chang SW, Huang YC, Lin LC, Yang JT, Weng HH, Tsai YH, Lee TH.
    • Ezetimibe-Simvastatin Therapy Reduce Recurrent Ischemic Stroke Risks in Type 2Diabetic Patients.
      J Clin Endocrinol Metab. 2016; 101(8):2994-3001.
      Liu CH, Chen TH, Lin MS, Hung MJ, Chung CM, Cherng WJ, Lee TH, Lin YS.
    • Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke.
      N Engl J Med. 2016 Jun 16;374(24):2313-23.
      Anderson CS, Robinson T, Lindley RI, Arima H, Lavados PM, Lee TH, Broderick JP, Chen X, Chen G, Sharma VK, Kim JS, Thang NH, Cao Y, Parsons MW, Levi C, Huang Y, Olavarria VV, Demchuk AM, Bath PM, Donnan GA, Martins S, Pontes-Neto OM, Silva F, Ricci S, Roffe C, Pandian J, Billot L, Woodward M, Li Q, Wang X, Wang J, Chalmers J; ENCHANTED Investigators and Coordinators.
    • A home-based training programme improves family caregivers' oral care practices with stroke survivors: a randomized controlled trial.
      Int J Dent Hyg 2016 May;14(2):82-91.
      Kuo YW, Yen M, Fetzer S, Chiang LC, Shyu YI, Lee TH, Ma HI.
    • Investigating cerebral oedema using poroelasticity.
      Med Eng Phys. 2016 Jan;38(1):48-57.
      Vardakis JC, Chou D, Tully BJ, Hung CC, Lee TH, Tsui PH, Ventikos Y.
    • Bladder Dysfunction Induced by Cerebral Hypoperfusion after Bilateral Common Carotid Artery Occlusion in Rats.
      Neurourol Urodyn 2015; 34:586–591.
      Liang CC, Lin YH, Liu HL, *Lee TH.
    • Carotid Artery Stenting Improves Cerebral Hemodynamics Regardless of the Flow Direction of Ophthalmic Artery.
      Angiology. 2015; 66(2):180-6.
      Liu CH, Chang CH, Chang TY, Huang KL, Lin Jr-Rung, Chen YW, Yip BS, Ryu SJ, Chang YJ, *Lee TH.
    • Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis.
      Neuropsychiatr Dis Treat. 2015;11:273-8.
      Chen CC, Chung CY, *Lee TH, Chang WH, Tang SF, Pei YC.
    • Recommendations from the international stroke genetics consortium, part2:biological sample collection and storage.
      Stroke. 2015 Jan;46(1):285-90.
      Battey TW, Valant V, Kassis SB, Kourkoulis C, Lee C, Anderson CD, Falcone GJ, Jimenez-Conde J, Fernandez-Cadenas I, Pare G, Rundek T, James ML, Lemmens R, Lee TH, Tatlisumak T, Kittner SJ, Lindgren A, Mateen FJ, Berkowitz AL, Holliday EG, Majersik J, Maguire J, Sudlow C, Rosand ; International Stroke Genetics Consortium.
    • Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis.
      Neuropsychiatr Dis Treat. 2015;11:273-8.
      Chen CC, Chung CY, Lee TH, Chang WH, Tang SF, Pei YC.
    • Rationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE study (ENCHANTED) trial: An international multicenter 2 x 2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment.
      Int J Stroke 2015 Jul;10(5):778-88.
      Huang Y, Sharma VK, Robinson T, Lindley RI, Chen X, Kim JS, Lavados P, Olavarria V, Arima H, Fuentes S, Nguyen HT, Lee TH, Parsons MW, Levi C, Demchuk AM, Bath PM, Broderick JP, Donnan GA, Martins S, Pontes-Neto OM, Silva F, Pandian J, Ricci S, Stapf C, Woodward M, Wang J, Chalmers J, Anderson CS. ENCHANTED investigators.
    • Presence of Gyriform Air Predicts Unfavorable Outcome in Venous Catheter-Related Cerebral Air Embolism.
      J Stroke Cerebrovasc Dis 2015 Oct;24(10):2189-95.
      Cheng CK, Chang TY, Liu CH, Chang CH, Huang KL, Chin SC, Wu HC, Chang YJ, Lee TH.
    • Evaluation of Anti-Inflammatory Effects of Helminthostachys zeylanica Extracts via Inhibiting Bradykinin-Induced MMP-9 Expression in Brain Astrocytes.
      Mol Neurobiol 2015 (2):1-11.
      Hsieh HL, Yang SH, Lee TH, Fang JY, Lin CF.
    • Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis.
      Neuropsychiatric Dis Treat. 2015; 11:273-8.
      Chen CC, Chung CY, Lee TH, Chang WH, Simon FT Tang, Pei YC.
    • Coexisting diseases of moyamoya vasculopathy.
      J Stroke Cerebrovasc Dis. 2014 ;23(6):1344-50.
      Wei YC, Liu CH, Chang TY, Chin SC, Chang CH, Huang KL, Chang YJ, Peng TI, *Lee TH.
    • Neuroprotective mechanism of BNG-1 against focal cerebral ischemia: a neuroimaging and neurotrophin study.
      PLoS One. 2014; 9(12):e114909.
      Chi NF, Liu HL, Yang JT, Lin JR, Liao SL, Peng BH, Lee YT, *Lee TH.
    • Impact of Coexisting Coronary Artery Disease on the Occurrence of Cerebral Ischemic Lesions after Carotid Stenting.
      Plos One. 2014; 9(4):e94280.
      Huang KL, ChangYJ, Chang CH, Chang TY, Liu CH, Hsieh IC, Wong HF, Wai YY, Chen YW, Yip BS, *Lee TH.
    • A Rat Model of Thermbosis in Common Carotid Artery Induced by Implantable Wireless Light-Emitting Diode Device.
      Biomed Res Int. 2014; 2014:724134.
      Yeh JC, Huang KL, Hsiao YC, Hsu YH, Lin YH,Lou SL, *Lee TH.
    • Perpartion and characterization of biocompatible and thrmoresponsive micells based on poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) grafted on polysuccinimide for drug delivery.
      Journal of biomat appl. 2014; 29(3):442-53.
      Yeh JC, Hsu YT, Su CM, Wang MC, *Lee TH, Lou SL.
    • Dehydration is an independent predictor of discharge outcome and admission cost in acute ischaemic stroke.
      Eur J Neurol 2014; 21(9):1184-1191.
      Liu CH,Lin SC, Lin JR, Yang JT, Chang YJ, Chang CH, Chang TY, Huang KL, Ryu SJ,*Lee TH.
    • Relationships between ophthalmic artery flow direction and cognitive performance in patients with unilateral carotid artery stenosis.
      J Neurol Sci. 2014;336(1-2): 184-190.
      Huang KL, Chang TY, Chang CH, Liu HL, Chang YJ, Liu CJ,*Lee TH, **Ho MY.
    • Longitudinal MR imaging study in the prediction of ischemic susceptibility after cerebral hypoperfusion in rats: Influence of aging and hypertension.
      Neuroscience 2014;257:31-40.
      Lee JT, Liu HL, Yang JT, Yang ST, Lin JR, *Lee TH.
    • The Reliability and Predictive Ability of a Biomarker of Oxidative DNA Damage on Functional Outcomes after Stroke Rehabilitation.
      In J Mol Sci. 2014; 15: 6504-6516.
      Hsieh YW, Lin KC, Korivi M, Lee TH, Wu CY, Wu KY.
    • Computer-Aided Diagnosis of Hyperacute Stroke with Thrombolysis Decision Support Using a Contralateral Comparative Method of CT Image Analysis.
      J Digit Imaging. 2014;DOI 10.1007/s10278-013-9672-x.
      Shieh Y, Chang CH, Shieh M, LeeTH, Chang YJ, Wong HF, Chin SC, Goodwin S.
    • Genetic Polymorphism of LDLR (rs688) Is Associated with Primary Intracerebral Hemorrhage.
      Curr Neurovasc Res. 2014;11(1):10-5.
      Lee JD, Hsiao KM, Lee TH, Kuo YW, Huang YC, Hsu HL, Lin YH, Wu CY, Huang YC, Lee M, Yang HT, Hsu CY, Pan YT.
    • Heterogeneous Cerebral Vasoreactivity Dynamics in Patients with Carotid Stenosis.
      Plos One 2013;8(9):e76072.
      Chang TY, Kuan WC, Huang KL, Chang CH, Chang YJ, Wong HF, *Lee TH, Liu HL.
    • Synthesis and characteristics of biodegradable and temperature responsive polymeric micelles based on poly(aspartic acid) -g-poly (N-isopropylacrylamide-co-N ,N-dimethylacrylamide).
      Colloids and Surfaces A: Physicochem. Eng. Aspects 2013;421:1-8.
      Yeh JC, Yang HH, Hsu YT, Su CM, *Lee TH, Lou SL.
    • Less favorable neurological recovery after acute stroke in patients with hypercholesterolemia.
      Clin Neurol Neurosurg. 2013;115(8): 1446-1450.
      Weng WC, Huang WY, Su FC, Chien YY, Wu CL, Lee T H, Peng TI.
    • Rapid progression and brain atrophy in anti-AMPA receptor encephalitis.
      J Neuroimmunol. 2013;261(1-2): 129-133.
      Wei YC, Liu CH, Lin JJ, Lin KJ, Huang KL, Lee TH, Chang YJ, Peng TI, Lin KL, Chang TY, Chang CH, Kuo HC, Chang KH, Cheng MY, Huang CC.
    • Effects of sex hormones on cell proliferation and apoptosis in the urinary bladder muscle of ovariectomized rat.
      Taiwan J Obstet Gynecol. 2013;52(3): 335-340.
      Liang CC, Lee TH, Chang SD.
    • Fire-heat and Qi deficiency syndromes as predictors of short-term prognosis of acute ischemic stroke.
      J Altern Complement Med. 2013;19(8): 721-728.
      Cheng SC, Lin CH, Chang YJ, Lee TH, Ryu SJ, Chen CH, Chang HK, Chang CJ, Hu WL, Hung YC.
    • Differential trajectory of functional recovery and determinants for first time stroke survivors by using a LCGA approach: a hospital based analysis over a 1-year period.
      Eur J Phys Rehabil Med. 2013;49(4)463-472.
      Huang HC, Chang CH, Lee TH, Chang YJ, Ryu SJ, Chang TY, Huang KL, Liu CH, Chang HJ.
    • The Impact Factors on the Cost and Length of Stay among Acute Ischemic Stroke.
      J Stroke Cerebrovasc Dis. 2013;22(7):152-158.
      Huang YC, Hu CJ, Lee TH, Yang JT, Weng HH, Lin LC, Lai SL.
    • The impact of intracranial carotid artery calcification on the development of thrombolysis-induced intracerebral hemorrhage.
      J Stroke Cerebrovasc Dis. 2013;22(8):e455-e462.
      Lin TC, Chao TH, Shieh Y, Lee TH, Chang Y J, Lee JD, Peng TI, Chang KC, Liou CW, Chang TY, Hung KL, Chang CH.
    • Brain computed tomography perfusion may help to detect hemodynamic reconstitution and predict intracerebral hemorrhage after carotid stenting.
      J Vasc Surg. 2012;56(5):1281-90.
      Chin SC, Chang CH , Chang TY, Huang KL, Wu TC, Lin JR, Chang YJ, *Lee TH.
    • Amyloid deposition after cerebral hypoperfusion: Evidenced on [(18)F]AV-45 positron emission tomography.
      J Neurol Sics. 2012;319:124-129.
      Huang KL, Lin KJ, Ho MY, Chang YJ, Chang CH, Wey SP, Hsieh CJ, Yen TC, Hsiao IT, *Lee TH.
    • Cervicocranial Fibromuscular Dysplasia in Taiwanese Ischemic Stroke Patients.
      Eur Neurol. 2012;67:129-135.
      Liu CH, Wu D, Chin SC, Fu SC, Wu TC, Chang CH, Peng TI, Chang YJ, *Lee TH.
    • Predictors of clinical deterioration during hospitalization following acute ischemic stroke.
      Eur Neurol. 2012;67(3): 186-192.
      Lin LC, Lee TH, Chang CH, Chang YJ, Liou CW, Chang KC, Lee JD, Peng TY, Chung J, Chen SC, Yang JT.
    • Symptomatic pulmonary embolism among stroke patients in Taiwan: a retrospective cohort study.
      Top Stroke Rehabil. 2012;19(5): 361-368.
      Chen CC, Lee TH, Chung CY, Chang WH, Hong JP, Huang LT, Tang SF, Chen CK.
    • Cost-effectiveness analysis of stroke management under a universal health insurance system.
      J Neurol Sci. 2012;323(1-2):205-215.
      Chang KC, Lee HC, Huang YC, Hung JW, Chiu HE, Chen JJ, Lee TH.
    • Polymorphisms at the LDLR Locus may be Associated with Ischemic Cerebrovascular Disease Independent of Lipid Profile.
      Curr Neurovasc Res. 2012;9(3):200-6.
      Lee JD, Lee TH, Kuo YW, Huang YC, Hsu HL, Lin YH, Wu CY, Huang YC, Lee M, Hsiao KM.
    • Paraoxonase-1 is not a major determinant of stent thrombosis in a Taiwanese population.
      Plos One 2012;7(6):e39178.
      Chen DY, Wang CY, Wen MS, Lee TH, Chu Y, Hsieh MJ, Chang SH, Lee CH, Wang JL, Chen CC, Lu LS, Lee MT, Yeh SJ, Lin FC, Hsieh IC.
    • Bronchorrhea following Stroke.
      Eur Neurol. 2012;67(1): 57-62.
      Sung CY, Lee TH, Chu NS.