您現在的位置 :

醫療團隊

專業的醫護人員，提供最佳的醫療服務

醫師介紹

  •

吳逸如醫師

巴金森氏症、肉毒桿菌素注射、肌張力不全、舞蹈症、顫抖症、脊髓小腦共濟失調症、遺傳性神經退化疾病、罕見疾病、神經肌肉疾病
  • 國語,英語,閩南語
  • 教授
醫師網路掛號
直接點選進入醫師網路掛號畫面
醫師資歷
  • 現職
    • 林口長庚紀念醫院神經內科部副部主任
    • 林口長庚紀念醫院神經內科教授級主治醫師
  • 學歷
    • 中山醫學院醫學系學士
  • 經歷
    • 現任亞太區動作障礙學會秘書長
    • 現任世界動作障礙學會教育委員
    • 現任世界動作障礙學會婦女特別研究小組共同主席
    • 罕見疾病審查專家
    • 曾任世界神經學會出版委員會委員
    • 曾任世界神經學會教育委員
    • 曾任亞太區動作障礙學會理事
    • 曾任亞太區動作障礙學會教育委員
    • 曾任台灣動作障礙學會理事長
    • 曾任林口長庚紀念醫院神經內科病房主任
    • 林口長庚紀念醫院神經內科主治醫師
    • 林口長庚紀念醫院神經內科住院醫師
  • 學會與認證
    • 台灣動作障礙學會理事長
    • 台灣神經學學會
    • 臺灣醫學會
    • 神經科專科醫師證書
    • 神經重症專科醫師證書
  • 論文及期刊發表
    • A New Phenotype of TUBB4A Mutation in a Family With Adult-Onset Progressive Spastic Paraplegia and Isolated Hypomyelination Leukodystrophy: A Case Report and Literature Review.
      J Mov Disord. 2024 Jan;17(1):94-98. doi: 10.14802/jmd.23142. Epub 2023 Oct 23.
      Pei-Chen Hsieh, Pei Shan Yu, Wen-Lang Fan, Chun-Chieh Wang, Chih-Ying Chao, Yih-Ru Wu*.
    • A fixel-based analysis of white matter reductions early detects Parkinson disease with mild cognitive impairment.
      Biomed J. 2023 Nov 8:100678. doi: 10.1016/j.bj.2023.100678. Online ahead of print.
      Ting-Wei Liao, Jiun-Jie Wang, Chih-Chien Tsai, Pei-Ning Wang, Yao-Liang Chen, Yi-Ming Wu, Yih-Ru Wu*.
    • Novel Compound Heterozygous Mutations in the SYNE1 Gene in a Taiwanese Family: A Case Report and Literature Review.
      J Mov Disord. 2023 May;16(2):202-206. doi: 10.14802/jmd.22105. Epub 2023 Apr 26.
      Chia-Yan Kuo, Pei Shan Yu, Chih-Ying Chao, Chun-Chieh Wang, Wen-Lang Fan, Yih-Ru Wu*.
    • Phosphorylated α-synuclein in diluted human serum as a biomarker for Parkinson's disease.
      Biomed J. 2022 Dec;45(6):914-922. doi: 10.1016/j.bj.2021.12.010. Epub 2021 Dec 31.
      Wei-Ru Chen, Jin-Chung Chen, Sheng-Yi Chang, Chi-Tse Chao, Yih-Ru Wu*, Chiung-Mei Chen*, Chien Chou*.
    • UQCRC1 variants in early-onset and familial Parkinson's disease in a Taiwanese cohort.
      Front Neurol. 2022 Dec 9:13:1090406. doi: 10.3389/fneur.2022.1090406. eCollection 2022.
      Ting-Wei Liao, Chih-Ying Chao, Yih-Ru Wu*.
    • Diagnosis and Clinical Features in Autoimmune-Mediated Movement Disorders.
      J Mov Disord. 2022 May;15(2):95-105. doi: 10.14802/jmd.21077. Epub 2022 May 26.
      Pei-Chen Hsieh, Yih-Ru Wu*.
    • Association of ITPKB, IL1R2 and COQ7 with Parkinson's disease in Taiwan.
      J Formos Med Assoc. 2022 Mar;121(3):679-686. doi: 10.1016/j.jfma.2021.06.016. Epub 2021 Jul 7.
      Hwa-Shin Fang, Chun-Chieh Wang, Chih-Ying Chao, Wen-Lang Fan, Shih-Chi Su, Yih-Ru Wu*.
    • Association of AXIN1 With Parkinson's Disease in a Taiwanese Population.
      J Mov Disord. 2022 Jan;15(1):33-37. doi: 10.14802/jmd.21073. Epub 2021 Nov 17.
      Hwa-Shin Fang, Chih-Ying Chao, Chun-Chieh Wang, Wen-Lang Fan, Po-Jung Huang, Hon-Chung Fung, Yih-Ru Wu*.
    • Fixel-Based Analysis Effectively Identifies White Matter Tract Degeneration in Huntington's Disease.
      Front Neurosci. 2021 Sep 13:15:711651. doi: 10.3389/fnins.2021.711651. eCollection 2021.
      Sher Li Oh, Chiung-Mei Chen, Yih-Ru Wu, Maria Valdes Hernandez, Chih-Chien Tsai, Jur-Shan Cheng, Yao-Liang Chen, Yi-Ming Wu, Yu-Chun Lin, Jiun-Jie Wang*.
    • Fibroblast Growth Factor 20 Gene Polymorphism in Parkinson's Disease in Asian Population: A Meta-Analysis.
      Genes (Basel). 2021 Apr 29;12(5):674. doi: 10.3390/genes12050674.
      Han-Lin Chiang, Yih-Ru Wu, Yi-Chun Chen, Hon-Chung Fung, Chiung-Mei Chen*.
    • Role of LRP10 in Parkinson's disease in a Taiwanese cohort.
      Parkinsonism Relat Disord. 2021 Jul 2;89:79-83. doi: 10.1016/j.parkreldis.2021.06.026. Online ahead of print.
      Ting-Wei Liao, Chun-Chieh Wang, Wen-Hung Chung, Shih-Chi Su, Szu-Han Chin, Hon Chung Fung, Yih-Ru Wu*.
    • Reappraisal of the incidence, various types and risk factors of malignancies in patients with dermatomyositis and polymyositis in Taiwan.
      Sci Rep. 2021 Feb 25;11(1):4545. doi: 10.1038/s41598-021-83729-5.
      Jung-Lung Hsu#, Ming-Feng Liao#, Chun-Che Chu, Hung-Chou Kuo, Rong-Kuo Lyu, Hong-Shiu Chang, Chiung-Mei Chen, Yih-Ru Wu, Kuo-Hsuan Chang, Yi-Ching Weng, Chun-Wei Chang, Hsing-I Chiang, Chih-Kuang Cheng, Pai-Wei Lee, Chin-Chang Huang, Long-Sun Ro*.
    • "Hot cross bun" is a potential imaging marker for the severity of cerebellar ataxia in MSA-C.
      NPJ Parkinson's Disease. 2021 Feb 15;7(1):15. doi: 10.1038/s41531-021-00159-w.
      Shuzhen Zhu, Bin Deng, Zifeng Huang, Zihan Chang, Hualin Li, Hui Liu, Yanjun Huang, Ying Pan, Yanping Wang, Yin-Xia Chao, Ling-Ling Chan, Yih-Ru Wu, Eng-King Tan*, Qing Wang*.
    • Pathomechanism Characterization and Potential Therapeutics Identification for Parkinson's Disease Targeting Neuroinflammation.
      Int J Mol Sci. 2021 Jan 21;22(3):1062. doi: 10.3390/ijms22031062.
      Chiung-Mei Chen, Chien-Yu Yen, Wan-Ling Chen, Chih-Hsin Lin, Yih-Ru Wu, Kuo-Hsuan Chang, Guey-Jen Lee-Chen*.
    • Association of SOD2 p.V16A polymorphism with Parkinson's disease: A meta-analysis in Han Chinese.
      J Formos Med Assoc. 2021 Jan;120(1 Pt 2):501-507. doi: 10.1016/j.jfma.2020.06.023. Epub 2020 Jun 30.
      Yih-Ru Wu, Kuo-Hsuan Chang, Chih-Ying Chao, Chih-Hsin Lin, Yi-Chun Chen, Tsai-Wei Liu, Guey-Jen Lee-Chen, Chiung-Mei Chen*.
    • Pathomechanism characterization and potential therapeutics identification for SCA3 targeting neuroinflammation.
      Aging (Albany NY). 2020 Nov 10;12(23):23619-23646. doi: 10.18632/aging.103700. Epub 2020 Nov 10.
      Ya-Jen Chiu, Shu-An Lin, Wan-Ling Chen, Te-Hsien Lin, Chih-Hsin Lin, Ching-Fa Yao, Wenwei Lin, Yih-Ru Wu, Kuo-Hsuan Chang, Guey-Jen Lee-Chen, Chiung-Mei Chen*.
    • Rare VPS35 A320V Variant in Taiwanese Parkinson's Disease Indicates Disrupted CI-MPR Sorting and Impaired Mitochondrial Morphology.
      Brain Sci. 2020 Oct 27;10(11):783. doi: 10.3390/brainsci10110783.
      Yih-Ru Wu, Chih-Hsin Lin, Chih-Ying Chao, Chia-Wen Chang, Chiung-Mei Chen*, Guey-Jen Lee-Chen*.
    • Serum levels of cell adhesion molecules in patients with neuromyelitis optica spectrum disorder.
      Ann Clin Transl Neurol. 2020 Oct;7(10):1854-1861. doi: 10.1002/acn3.51167. Epub 2020 Aug 28.
      Bao-Luen Chang, Long-Sun Ro, Chiung-Mei Chen, Yen-Shi Lo, Rong-Kuo Lyu, Hung-Chou Kuo, Ming-Feng Liao, Chun-Wei Chang, Hong-Shiu Chang, Ching-Chang Huang, Yih-Ru Wu, Chun-Che Chu, Yi-Ching Weng, Kuo-Hsuan Chang*.
    • Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study.
      JAMA Neurol. 2020 Jun 1;77(6):746-754. doi: 10.1001/jamaneurol.2020.0428.
      Jia Nee Foo, Elaine Guo Yan Chew, Sun Ju Chung, Rong Peng, Cornelis Blauwendraat, Mike A Nalls, Kin Y Mok, Wataru Satake, Tatsushi Toda, Yinxia Chao, Louis C S Tan, Moses Tandiono, Michelle M Lian, Ebonne Y Ng, Kumar-M Prakash, Wing-Lok Au, Wee-Yang Meah, Shi Qi Mok, Azlina Ahmad Annuar, Anne Y Y Chan, Ling Chen, Yongping Chen, Beom S Jeon, Lulu Jiang, Jia Lun Lim, Juei-Jueng Lin, Chunfeng Liu, Chengjie Mao, Vincent Mok, Zhong Pei, Hui-Fang Shang, Chang-He Shi, Kyuyoung Song, Ai Huey Tan, Yih-Ru
    • Lactulose and Melibiose Attenuate MPTP-Induced Parkinson's Disease in Mice by Inhibition of Oxidative Stress, Reduction of Neuroinflammation and Up-Regulation of Autophagy.
      Front Aging Neurosci. 2020 Jul 24;12:226. doi: 10.3389/fnagi.2020.00226. eCollection 2020.
      Chih-Hsin Lin, Pei-Cih Wei, Chiung-Mei Chen, Yu-Ting Huang, Jia-Lan Lin, Yen-Shi Lo, Jia-Li Lin, Chung-Yin Lin, Yih-Ru Wu, Kuo-Hsuan Chang*, Guey-Jen Lee-Chen*.
    • Exploration of multi-target effects of 3-benzoyl-5-hydroxychromen-2-one in Alzheimer's disease cell and mouse models.
      Aging Cell. 2020 Jul;19(7):e13169. doi: 10.1111/acel.13169. Epub 2020 Jun 4.
      Te-Hsien Lin, Ya-Jen Chiu, Chih-Hsin Lin, Chung-Yin Lin, Chih-Ying Chao, Yu-Chieh Chen, Shu-Mei Yang, Wenwei Lin, Hsiu Mei Hsieh-Li, Yih-Ru Wu, Kuo-Hsuan Chang, Guey-Jen Lee-Chen, Chiung-Mei Chen*.
    • Lactulose and Melibiose Inhibit α-Synuclein Aggregation and Up-Regulate Autophagy to Reduce Neuronal Vulnerability.
      Cells. 2020 May 16;9(5):1230. doi: 10.3390/cells9051230.
      Chiung Mei Chen, Chih-Hsin Lin, Yih-Ru Wu, Chien-Yu Yen, Yu-Ting Huang, Jia-Lan Lin, Chung-Yin Lin, Wan-Ling Chen, Chih-Ying Chao, Guey-Jen Lee-Chen*, Ming-Tsan Su*, Kuo-Hsuan Chang*.
    • Variants in saposin D domain of prosaposin gene linked to Parkinson's disease.
      Brain. 2020 Apr 1;143(4):1190-1205. doi: 10.1093/brain/awaa064.
      Yutaka Oji, Taku Hatano, Shin-Ichi Ueno, Manabu Funayama, Kei-Ichi Ishikawa, Ayami Okuzumi, Sachiko Noda, Shigeto Sato, Wataru Satake, Tatsushi Toda, Yuanzhe Li, Tomoko Hino-Takai, Soichiro Kakuta, Taiji Tsunemi, Hiroyo Yoshino, Kenya Nishioka, Tatsuya Hattori, Yasuaki Mizutani, Tatsuro Mutoh, Fusako Yokochi, Yuta Ichinose, Kishin Koh, Kazumasa Shindo, Yoshihisa Takiyama, Tsuyoshi Hamaguchi, Masahito Yamada, Matthew J Farrer, Yasuo Uchiyama, Wado Akamatsu, Yih-Ru Wu , Junko Matsuda, Nobutaka Hat
    • New Synthetic 3-Benzoyl-5-Hydroxy-2 H-Chromen-2-One (LM-031) Inhibits Polyglutamine Aggregation and Promotes Neurite Outgrowth through Enhancement of CREB, NRF2, and Reduction of AMPK α in SCA17 Cell Models.
      Oxid Med Cell Longev. 2020 Apr 22;2020:3129497. doi: 10.1155/2020/3129497. eCollection 2020.
      Chiung-Mei Chen, Wan-Ling Chen, Shu-Ting Yang, Te-Hsien Lin, Shu-Mei Yang, Wenwei Lin, Chih-Ying Chao, Yih-Ru Wu, Kuo-Hsuan Chang, Guey-Jen Lee-Chen*.
    • Genetic Analysis of EGLN1 C127S Variant in Taiwanese Parkinson's Disease.
      Parkinsons Dis. 2020 Apr 25;2020:9582317. doi: 10.1155/2020/9582317. eCollection 2020.
      Han-Lin Chiang, Chiung Mei Chen, Yi-Chun Chen, Chih-Ying Chao, Yih-Ru Wu*, Guey-Jen Lee-Chen*.
    • Association of genetic variants within HLA-DR region with Parkinson's disease in Taiwan.
      Neurobiol Aging. 2020 Mar;87:140.e13-140.e18. doi: 10.1016/j.neurobiolaging.2019.11.002. Epub 2019 Nov 9.
      Kuo-Hsuan Chang, Yih-Ru Wu, Yi-Chun Chen, Hon-Chung Fung, Chiung-Mei Chen*.
    • Association of RIT2 and RAB7L1 with Parkinson's disease: a case-control study in a Taiwanese cohort and a meta-analysis in Asian populations.
      Neurobiol Aging. 2020 Mar;87:140.e5-140.e11. doi: 10.1016/j.neurobiolaging.2019.11.001. Epub 2019 Nov 9.
      Tsai-Wei Liu, Yih-Ru Wu, Yi-Chun Chen, Hon Chung Fung, Chiung-Mei Chen*.
    • Delivering patient-centered care in Parkinson's disease: Challenges and consensus from an international panel.
      Parkinsonism Relat Disord. 2020 Mar;72:82-87. doi: 10.1016/j.parkreldis.2020.02.013. Epub 2020 Feb 27.
      Roongroj Bhidayasiri, Pattamon Panyakaew, Claudia Trenkwalder, Beomseok Jeon, Nobutaka Hattori, Priya Jagota, Yih-Ru Wu, Elena Moro, Shen-Yang Lim, Huifang Shang, Raymond Rosales, Jee-Young Lee, Win Min Thit, Eng-King Tan, Thien Thien Lim, Ngoc Tai Tran, Nguyen Thanh Binh, Appasone Phoumindr, Thanatat Boonmongkol, Onanong Phokaewvarangkul, Yuwadee Thongchuam, Somchit Vorachit, Rachaneewan Plengsri, Marisa Chokpatcharavate, Hubert H Fernandez.
    • Plasma and Serum Alpha-Synuclein as a Biomarker of Diagnosis in Patients With Parkinson's Disease.
      Frontiers in Neurology. 21 January 2020; 10:1388. doi: 10.3389/fneur.2019.01388.
      Chang CW, Yang SY, Yang CC, Chang CW, Wu YR*.
    • Does the M.D. Anderson Dysphagia Inventory correlate with dysphagia-limit and the Unified Parkinson Disease Rating Scale in early-stage Parkinson's disease?
      J Formos Med Assoc. 2020 Jan;119(1 Pt 2):247-253. doi: 10.1016/j.jfma.2019.05.005. Epub 2019 May 24.
      Wang CM, Tsai TT, Wang SH, Wu YR*.
    • Neuroprotection of Indole-Derivative Compound NC001-8 by the Regulation of the NRF2 Pathway in Parkinson's Disease Cell Models.
      Oxid Med Cell Longev. 2019 Oct 31;2019:5074367. doi: 10.1155/2019/5074367. eCollection 2019.
      Wei PC, Lee-Chen GJ, Chen CM, Wu YR, Chen YJ, Lin JL, Lo YS, Yao CF, Chang KH*.
    • Acupuncture Effect and Mechanism for Treating Pain in Patients With Parkinson's Disease.
      Front Neurol. 2019 Oct 22;10:1114. doi: 10.3389/fneur.2019.01114. eCollection 2019.
      Yu SW, Lin SH, Tsai CC, Chaudhuri KR, Huang YC, Chen YS, Yeh BY, Wu YR*, Wang JJ*.
    • Association between CSF1 and CSF1R Polymorphisms and Parkinson's Disease in Taiwan.
      J. Clin. Med. 2019, 8(10), 1529; https://doi.org/10.3390/jcm8101529 (registering DOI) - 24 Sep 2019.
      Kuo-Hsuan Chang, Yih-Ru Wu, Yi-Chun Chen, Hsiu-Chuan Wu, Chiung-Mei Chen*.
    • CCM1 and CCM2 variants in patients with cerebral cavernous malformation in an ethnically Chinese population in Taiwan.
      Sci Rep. 2019 Aug 27;9(1):12387. doi: 10.1038/s41598-019-48448-y.
      Chang CW, Hsu PW, Wei KC, Chang CW, Fung HC, Hsih MS, Hsu WC, Ro LS, Chang CN, Wang JJ, Wu YR*, Chen ST*.
    • Parkinson's disease in the Western Pacific Region.
      Lancet Neurol. 2019 Sep;18(9):865-879. doi: 10.1016/S1474-4422(19)30195-4. Epub 2019 Jun 4.
      Lim SY*, Tan AH, Ahmad-Annuar A, Klein C, Tan LCS, Rosales RL, Bhidayasiri R, Wu YR, Shang HF, Evans AH, Pal PK, Hattori N, Tan CT, Jeon B, Tan EK, Lang AE.
    • Using global team science to identify genetic parkinson's disease worldwide.
      Ann Neurol. 2019 Aug;86(2):153-157. doi: 10.1002/ana.25514. Epub 2019 Jun 26.
      Vollstedt EJ, Kasten M, Klein C; MJFF Global Genetic Parkinson's Disease Study Group: Wu YR.
    • Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington's disease.
      Nat Commun. 2019 Aug 2;10(1):3473. doi: 10.1038/s41467-019-11441-0.
      Siew JJ, Chen HM, Chen HY, Chen HL, Chen CM, Soong BW, Wu YR, Chang CP, Chan YC, Lin CH, Liu FT, Chern Y*.
    • POLG R964C and GBA L444P mutations in familial Parkinson's disease: Case report and literature review.
      Brain Behav. 2019 May;9(5):e01281. doi: 10.1002/brb3.1281. Epub 2019 Apr 2.
      Hsieh PC, Wang CC, Tsai CL, Yeh YM, Lee YS, Wu YR*.
    • Anxiety and Levodopa Equivalent Daily Dose Are Potential Predictors of Sleep Quality in Patients With Parkinson Disease in Taiwan.
      Frontiers in Neurology. 10:340. doi: 10.3389/fneur.2019.00340
      Chang C-W, Fan J-Y, Chang B-L, Wu Y-R*
    • Shaoyao Gancao Tang (SG-Tang), a formulated Chinese medicine, reduces aggregation and exerts neuroprotection in spinocerebellar ataxia type 17 (SCA17) cell and mouse models.
      Aging (Albany NY). 2019 Feb 13;11(3):986-1007. doi: 10.18632/aging.101804.
      Chen CM, Chen WL, Hung CT, Lin TH, Lee MC, Chen IC, Lin CH, Chao CY, Wu YR, Chang KH, Hsieh-Li HM, Lee-Chen GJ*.
    • J Alzheimers Dis. 2019;67(2):737-756. doi: 10.3233/JAD-180643.
      Indole Compound NC009-1 Augments APOE and TRKA in Alzheimer's Disease Cell and Mouse Models for Neuroprotection and Cognitive Improvement.
      Chen YC, Chiu YJ, Lin CH, Hsu WC, Wu JL, Huang CH, Lin CW, Yao CF, Huang HJ, Lo YS, Chen CM, Wu YR, Chang KH*, Lee-Chen GJ*, Mei Hsieh-Li H*.
    • Targeting Ubiquitin Proteasome Pathway with Traditional Chinese Medicine for Treatment of Spinocerebellar Ataxia Type 3.
      Am J Chin Med. 2019;47(1):63-95. doi: 10.1142/S0192415X19500046. Epub 2019 Jan 7.
      Chen IC, Chang CN, Chen WL, Lin TH, Chao CY, Lin CH, Lin HY, Cheng ML, Chiang MC, Lin JY, Wu YR, Lee-Chen GJ, Chen CM*.
    • Polymorphisms of ACMSD-TMEM163, MCCC1, and BCKDK-STX1B Are Not Associated with Parkinson's Disease in Taiwan.
      Parkinsons Dis. 2019 Jan 2;2019:3489638. doi: 10.1155/2019/3489638. eCollection 2019.
      Chang KH, Chen CM, Chen YC, Fung HC, Wu YR*.
    • Formulated Chinese Medicine Shaoyao Gancao Tang Reduces Tau Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation.
      Oxid Med Cell Longev. 2018 Oct 28;2018:9595741. doi: 10.1155/2018/9595741. eCollection 2018.
      Chen IC, Lin TH, Hsieh YH, Chao CY, Wu YR, Chang KH, Lee MC, Lee-Chen GJ, Chen CM*.
    • Home-Based Orolingual Exercise Improves the Coordination of Swallowing and Respiration in Early Parkinson Disease: A Quasi-Experimental Before-and-After Exercise Program Study.
      Front Neurol. 2018 Jul 30;9:624. doi: 10.3389/fneur.2018.00624. eCollection 2018.
      Wang CM, Shieh WY, Ho CS, Hu YW, Wu YR*.
    • Alternations of Metabolic Profile and Kynurenine Metabolism in the Plasma of Parkinson's Disease.
      Mol Neurobiol. 2018 Aug;55(8):6319-6328. doi: 10.1007/s12035-017-0845-3. Epub 2018 Jan 2.
      Chang KH, Cheng ML, Tang HY, Huang CY, Wu YR, Chen CM*.
    • Predictive Factors for Early Initiation of Artificial Feeding in Patients With Sporadic Creutzfeldt-Jakob Disease.
      Front. Neurol. 2018 Jul 3;9:496. doi: 10.3389/fneur.2018.00496.
      Hsieh PC, Li HT, Chang CW, Wu YR, Kuo HC*.
    • Analysis of GWAS-linked variants in multiple system atrophy.
      Neurobiol Aging. 2018 Jul;67:201.e1-201.e4. doi: 10.1016/j.neurobiolaging.2018.03.018. Epub 2018 Mar 23.
      Gu X, Chen Y, Zhou Q, Lu YC, Cao B, Zhang L, Kuo MC, Wu YR, Wu RM, Tan EK, Shang HF; Asian Multiple System Atrophy Consortium (AMSAC).
    • The indole compound NC009-1 inhibits aggregation and promotes neurite outgrowth through enhancement of HSPB1 in SCA17 cells and ameliorates the behavioral deficits in SCA17 mice.
      Neurotoxicology. 2018 Jun 21;67:259-269. doi: 10.1016/j.neuro.2018.06.009. [Epub ahead of print]
      Chen CM, Chen WL, Hung CT, Lin TH, Chao CY, Lin CH, Wu YR, Chang KH, Yao CF, Lee-Chen GJ*, Su MT*, Hsieh-Li HM*.
    • Genetic and functional characters of GRN p.T487I mutation in Taiwanese patients with atypical parkinsonian disorders.
      Parkinsonism Relat Disord. 2018 Jun;51:61-66. doi: 10.1016/j.parkreldis.2018.02.045. Epub 2018 Feb 28.
      Chang KH, Lee GC, Huang CC, Kuo HC, Chen CM, Hsiao YC, Hsu HC, Hsu KJ, Lin CH, Chang CW, Lee-Chen GJ, Wu YR*.
    • Catechol-O-methyltransferase (COMT) genetic variants are associated with cognitive decline in patients with Parkinson's disease.
      Parkinsonism Relat Disord. 2018 May;50:48-53. doi: 10.1016/j.parkreldis.2018.02.015. Epub 2018 Feb 9.
      Lin CH, Fan JY, Lin HI, Chang CW, Wu YR*.
    • DLG2, but not TMEM229B, GPNMB, and ITGA8 polymorphism, is associated with Parkinson's disease in a Taiwanese population.
      Neurobiol Aging. 2018 Apr;64:158.e1-158.e6. doi: 10.1016/j.neurobiolaging.2017.11.016. Epub 2017 Dec 8.
      Wu HC, Chen CM, Chen YC, Fung HC, Chang KH, Wu YR*.
    • Atypical presentation of dopa-responsive dystonia in Taiwan.
      Brain Behav. 2018 Jan 20;8(2):e00906. doi: 10.1002/brb3.906. eCollection 2018 Feb.
      Weng YC, Wang CC, Wu YR*.
    • Elevated serum levels of endothelin-1 in patients with chronic inflammatory demyelinating polyneuropathy.
      Clinica Chimica Acta.2018 Jan;476:49-53.
      Chang CW, Wu HC, Lyu RK, Lo YS, Chen CM, Ro LS, Chang HS, Huang CC, Liao MF, Wu YR, Kuo HC, Chu CC, Weng YC, Wei PT, Lo AL, Chang KH*.
    • Down-regulation of miR-9* in the peripheral leukocytes of Huntington's disease patients.
      Orphanet J Rare Dis. 2017 Dec 19;12(1):185. doi: 10.1186/s13023-017-0742-x.
      Chang KH, Wu YR, Chen CM*.
    • Altered Aconitase 2 Activity in Huntington's Disease Peripheral Blood Cells and Mouse Model Striatum.
      Int J Mol Sci. 2017 Nov 21;18(11). pii: E2480. doi: 10.3390/ijms18112480.
      Chen CM*, Wu YR, Chang KH.
    • Non-invasive assessment determine the swallowing and respiration dysfunction in early Parkinson's disease.
      Parkinsonism Relat Disord. 2017 Sep;42:22-27. doi: 10.1016/j.parkreldis.2017.05.024. Epub 2017 May 26.
      Wang CM, Shieh WY, Weng YH, Hsu YH, Wu YR*.
    • Depression and Catechol-O-methyltransferase (COMT) genetic variants are associated with pain in Parkinson's disease.
      Sci Rep. 2017 Jul 24;7(1):6306.
      Lin CH, Chaudhuri KR, Fan JY, Ko CI, Rizos A, Chang CW, Lin HI, Wu YR*.
    • Cross-Cultural Differences of the Non-Motor Symptoms Studied by the Traditional Chinese Version of the International Parkinson and Movement Disorder Society- Unified Parkinson's Disease Rating Scale.
      Mov Disord Clin Pract. 2017;4:68-77.
      Yu RL, Wu RM, Chan AY, Mok V, Wu YR, Tilley BC, Luo S, Wang L, LaPelle NR, Stebbins GT, Goetz CG.
    • Patterns of False Memory in Patients with Huntington's Disease.
      Arch Clin Neuropsychol. 2017 Jun 1;32(4):391-400.
      Chen IW, Chen CM, Wu YR, Hua MS.
    • Targeting ENT1 and adenosine tone for the treatment of Huntington's disease.
      Hum Mol Genet. 2017 Feb 1;26(3):467-478.
      Kao YH, Lin MS, Chen CM, Wu YR, Chen HM, Lai HL, Chern Y, Lin CJ.
    • Genome-wide association study of Parkinson's disease in East Asians.
      Hum Mol Genet. 2017 Jan 1;26(1):226-232.
      Foo JN, Tan LC, Irwan ID, Au WL, Low HQ, Prakash KM, Ahmad-Annuar A, Bei J, Chan AY, Chen CM, Chen YC, Chung SJ, Deng H, Lim SY, Mok V, Pang H, Pei Z, Peng R, Shang HF, Song K, Tan AH, Wu YR, Aung T, Cheng CY, Chew FT, Chew SH, Chong SA, Ebstein RP, Lee J, Saw SM, Seow A, Subramaniam M, Tai ES, Vithana EN, Wong TY, Heng KK, Meah WY, Khor CC, Liu H, Zhang F, Liu J, Tan EK.
    • Medicinal herbs Oenanthe javanica (Blume) DC., Casuarina equisetifolia L. and Sorghum bicolor (L.) Moench protect human cells from MPP+ damage via inducing FBXO7 expression.
      Phytomedicine. 2016 Nov 15;23(12):1422-1433.
      Chen CM, Chen IC, Chen YL, Lin TH, Chen WL, Chao CY, Wu YR, Lu YT, Lee CY, Chien HC, Chen TS, Lee-Chen GJ, Lee CM.
    • Positive Effects of Specific Exercise and Novel Turning-based Treadmill Training on Turning Performance in Individuals with Parkinson's disease: A Randomized Controlled Trial.
      Sci Rep. 2016;6:33242.
      Cheng FY, Yang YR, Chen LM, Wu YR, Cheng SJ, Wang RY.
    • Increased serum concentrations of transforming growth factor-β1 (TGF-β1) in patients with Guillain-Barre syndrome.
      Clin Chim Acta. 2016;461:8-13.
      Chang KH, Lyu RK, Ro YS, Chen YC, Ro LS, Chang HS, Huang CC, Liao MF, Wu YR, Kuo HC, Chu CC, Chen CM.
    • The Potential of Indole/Indolylquinoline Compounds in Tau Misfolding Reduction by Enhancement of HSPB1.
      CNS Neurosci Ther. 2016 Jul 18. doi: 10.1111/cns.12592.
      Chang KH, Lin CH, Chen HC, Huang HY, Chen SL, Lin TH, Ramesh C, Huang CC, Fung HC, Wu YR, Huang HJ, Lee-Chen GJ, Hsieh-Li HM, Yao CF.
    • Relationships among Depression, Anxiety, Sleep, and Quality of Life in Patients with Parkinson's Disease in Taiwan.
      Parkinsons Dis. 2016;2016:4040185.
      Fan JY, Chang BL, Wu YR*.
    • Functional properties of LRRK2 mutations in Taiwanese Parkinson disease.
      J Formos Med Assoc. 2016 Jul 13. pii: S0929-6646(16)30110-3.
      Chang KH, Chen CM, Lin CH, Chang WT, Jiang PR, Hsiao YC, Wu YR, Lee-Chen GJ.
    • Identifying GSK-3β kinase inhibitors of Alzheimer's disease: Virtual screening, enzyme, and cell assays.
      Eur J Pharm Sci. 2016 Jun 30;89:11-9.
      Lin CH, Hsieh YS, Wu YR, Hsu CJ, Chen HC, Huang WH, Chang KH, Hsieh-Li HM, Su MT, Sun YC, Lee GC, Lee-Chen GJ.
    • Metabolic disturbances in plasma as biomarkers for Huntington's disease.
      J Nutr Biochem. 2016 May;31:38-44.
      Cheng ML, Chang KH, Wu YR, Chen CM.
    • The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer's disease.
      Drug Des Devel Ther. 2016;10:885-96.
      Chang KH, Chen IC, Lin HY, Chen HC, Lin CH, Lin TH, Weng YT, Chao CY, Wu YR, Lin JY, Lee-Chen GJ, Chen CM.
    • Associations of Matrix Metalloproteinase-9 and Tissue Inhibitory Factor-1 Polymorphisms With Parkinson Disease in Taiwan.
      Medicine (Baltimore). 2016;95:e2672.
      Chen YC, Wu YR, Mesri M, Chen CM.
    • Association of GCH1 and MIR4697, but not SIPA1L2 and VPS13C polymorphisms, with Parkinson's disease in Taiwan.
      Neurobiol Aging. 2015 Dec 30. pii: S0197-4580(15)00632-6.
      Chen CM, Chen YC, Chiang MC, Fung HC, Chang KH, Lee-Chen GJ, Wu YR.
    • Impairment of proteasome and anti-oxidative pathways in the induced pluripotent stem cell model for sporadic Parkinson's disease.
      Parkinsonism Relat Disord. 2016 Mar;24:81-8.
      Chang KH, Lee-Chen GJ, Wu YR, Chen YJ, Lin JL, Li M, Chen IC, Lo YS, Wu HC, Chen CM.
    • Memory for gist and detail information in patients with Parkinson's disease.
      BMJ Open. 2015 Nov 20;5(11):e009795.
      Yu RL, Tan CH, Wu YR, Wu RM, Chiu MJ, Hua MS.
    • Eukaryotic translation initiation factor 4-γ, 1 gene mutations are rare in Parkinson's disease among Taiwanese.
      J Formos Med Assoc. 2015 Oct 17. pii: S0929-6646(15)00276-4.
      Weng YC, Chen CM, Chen YC, Fung HC, Chang CW, Chang KH, Wu YR*.
    • STK39, But Not BST1, HLA-DQB1, and SPPL2B Polymorphism, Is Associated With Han-Chinese Parkinson's Disease in Taiwan.
      Medicine (Baltimore). 2015 Oct;94(41):e1690.
      Chang KH, Wu YR, Chen YC, Fung HC, Lee-Chen GJ, Chen CM.
    • Novel Lactulose and Melibiose Targeting Autophagy to Reduce PolyQ Aggregation in Cell Models of Spinocerebellar Ataxia 3.
      CNS Neurol Disord Drug Targets. 2016;15(3):351-9.
      Lin CH, Wu YR(co first author), Yang JM, Chen WL, Chao CY, Chen IC, Lin TH, Wu YC, Hsu KC, Chen CM, Lee GC, Hsieh-Li HM, Lee CM, Lee-Chen GJ.
    • Integrated non-invasive measurements reveal swallowing and respiration coordination recovery after unilateral stroke.
      Neurogastroenterol Motil. 2015 Oct;27(10):1398-408.
      Wang CM, Shieh WY, Chen JY, Wu YR.
    • High Protein Diet and Huntington's Disease.
      PLoS One. 2015 May 19;10(5):e0127654.
      Chen CM, Lin YS, Wu YR, Chen P, Tsai FJ, Yang CL, Tsao YT, Chang W, Hsieh IS, Chern Y, Soong BW.
    • Protein Kinase Cη Polymorphism and the Susceptibility to Ischemic Stroke in the Taiwan Population.
      Biomed J. 2015 Apr 22. doi: 10.4103/2319-4170.
      Chen YC, Huang CJ, Chen P, Wu YR, Shie SS, Chen ST, Lee-Chen GJ, Chen CM.
    • The potential of lactulose and melibiose, two novel trehalase-indigestible and autophagy-inducing disaccharides, for polyQ-mediated neurodegenerative disease treatment.
      Neurotoxicology. 2015 May;48:120-30.
      Lee GC, Lin CH, Tao YC, Yang JM, Hsu KC, Huang YJ, Huang SH, Kung PJ, Chen WL, Wang CM, Wu YR, Chen CM, Lin JY, Hsieh-Li HM, Lee-Chen GJ.
    • Wegener's granulomatosis with nervous system involvement: a hospital-based study.
      Eur Neurol. 2015;73(3-4):197-204.
      Huang YH, Ro LS, Lyu RK, Chang HS, Wu YR, Chang KH, Kuo HC.
    • Clinical and radiological findings suggesting disorders other than tolosa-hunt syndrome among ophthalmoplegic patients: a retrospective analysis.
      Headache. 2015 Feb;55(2):252-64.
      Hung CH, Chang KH, Chen YL, Wu YM, Lai CL, Chang HS, Lyu RK, Wu YR, Chen CM, Huang CC, Chu CC, Chen CH, Ro LS.
    • Virtual Reality-Based Training to Improve Obstacle-Crossing Performance and Dynamic Balance in Patients With Parkinson's Disease.
      Neurorehabil Neural Repair. 2015 Aug;29(7):658-6.
      Liao YY, Yang YR, Cheng SJ, Wu YR, Fuh JL, Wang RY.
    • Comparison between the cranial magnetic resonance imaging features of neuromyelitis optica spectrum disorder versus multiple sclerosis in Taiwanese patients.
      BMC Neurol. 2014; 14:218.
      Liao MF, Chang KH, Lyu RK, Huang CC, Chang HS, Wu YR, Chen CM, Chu CC, Kuo HC, Ro LS.
    • Clinical correlations of motor and somatosensory evoked potentials in neuromyelitis optica.
      PLoS One. 2014 Nov 25;9(11):e113631.
      Tsao WC, Lyu RK, Ro LS, Lao MF, Chen CM, Wu YR, Huang CC, Chang HS, Kuo HC, Chu CC, Chang KH.
    • High frequency of SPG4 in Taiwanese families with autosomal dominant hereditary spastic paraplegia.
      BMC Neurol. 2014;14:216.
      Lan MY, Chang YY, Yeh TH, Lai SC, Liou CW, Kuo HC, Wu YR, Lyu RK, Hung JW, Chang YC, Lu CS
    • Plasma inflammatory biomarkers for Huntington's disease patients and mouse model.
      Brain Behav Immun. 2014 Sep 28. pii: S0889-1591(14)00464-4.
      Chang KH, Wu YR, Chen YC, Chen CM.
    • The potential of indole and a synthetic derivative for polyQ aggregation reduction by enhancement of the chaperone and autophagy systems.
      ACS Chem Neurosci. 2014 Oct 15;5(10):1063-74.
      Lin CH, Wu YR(co-first author), Kung PJ, Chen WL, Lee LC, Lin TH, Chao CY, Chen CM, Chang KH, Janreddy D, Lee-Chen GJ, Yao CF.
    • Taiwan Severe Cutaneous Adverse Reaction Consortium; Japan Pharmacogenomics Data Science Consortium. Genetic variants associated with phenytoin-related severe cutaneous adverse reactions.
      JAMA. 2014 Aug 6;312(5):525-34.
      Chung WH, Chang WC, Lee YS, Wu YY, Yang CH, Ho HC, Chen MJ, Lin JY, Hui RC, Ho JC, Wu WM, Chen TJ, Wu T, Wu YR, Hsih MS, Tu PH, Chang CN, Hsu CN, Wu TL, Choon SE, Hsu CK, Chen DY, Liu CS, Lin CY, Kaniwa N, Saito Y, Takahashi Y, Nakamura R, Azukizawa H, Shi Y, Wang TH, Chuang SS, Tsai SF, Chang CJ, Chang YS, Hung SI.
    • FBXO7 Y52C Polymorphism as a Potential Protective Factor in Parkinson's Disease.
      PLoS One. 2014;9:e101392.
      Chen CM, Chen IC, Huang YC, Juan HF, Chen YL, Chen YC, Lin CH, Lee LC, Lee CM, Lee-Chen GJ, Lai YJ, Wu YR*.
    • Structural study of the microtubule-associated protein tau locus of Alzheimer's disease in Taiwan.
      Biomed J. 2014: 37:127-32.
      Chang CW, Hsu WC, Pittman A, Wu YR, Hardy J, Fung HC.
    • Tract-based spatial statistics: application to mild cognitive impairment.
      Biomed Res Int. 2014;2014:713079.
      Wai YY, Hsu WC, Fung HC, Lee JD, Chan HL, Tsai ML, Lin YC, Wu YR, Ying L, Wang JJ.
    • Factors influencing turning and its relationship with falls in individuals with Parkinson's disease.
      PLoS One. 2014 Apr 3;9(4):e93572.
      Cheng FY, Yang YR, Wang CJ, Wu YR, Cheng SJ, Wang HC, Wang RY.
    • Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease.
      Hum Mol Genet. 2014 Aug 15;23(16): 4328-44.
      Hsiao HY, Chiu FL, Chen CM, Wu YR, Chen HM, Chen YC, Kuo HC, Chern Y.
    • Aqueous extract of Glycyrrhiza inflata inhibits aggregation by upregulating PPARGC1A and NFE2L2-ARE pathways in cell models of spinocerebellar ataxia 3.
      Free Radic Biol Med. 2014 Jun;71:339-50.
      Chen CM, Weng YT, Chen WL, Lin TH, Chao CY, Lin CH, Chen IC, Lee LC, Lin HY, Wu YR, Chen YC, Chang KH, Tang HY, Cheng ML, Lee-Chen GJ, Lin JY.
    • Variant R244H in Na+/Mg2+ exchanger SLC41A1 in Taiwanese Parkinson's disease is associated with loss of Mg2+ efflux function. Parkinsonism Relat Disord.
      2014 Jun;20(6):600-3.
      Lin CH, Wu YR(co first author), Chen WL, Wang HC, Lee CM, Lee-Chen GJ, Chen CM.
    • Factors influencing obstacle crossing performance in patients with Parkinson's disease.
      PLoS One. 2014;9(1):e84245.
      Liao YY, Yang YR, Wu YR, Wang RY.
    • Aqueous extract of Gardenia jasminoides targeting oxidative stress to reduce polyQ aggregation in cell models of spinocerebellar ataxia 3.
      Neuropharmacology. 2014 ;81C:166-175.
      Chang KH, Chen WL, Wu YR(co first author), Lin TH, Wu YC, Chao CY, Lin JY, Lee LC, Chen YC, Lee-Chen GJ, Chen CM.
    • Downregulation of proteins involved in the endoplasmic reticulum stress response and Nrf2-ARE signaling in lymphoblastoid cells of spinocerebellar ataxia type 17.
      J Neural Transm. 2014;121:601-10.
      Lee LC, Weng YT, Wu YR, Soong BW, Tseng YC, Chen CM, Lee-Chen GJ.
    • Genetic Variants ofLRRK2 in Taiwanese Parkinson's Disease.
      PLoS One. 2013 Dec 5;8(12):e82001.
      Wu YR, Chang KH, Chang WT, Hsiao YC, Hsu HC, Jiang PR, Chen YC, Chao CY, Chang YC, Lee BH, Hu FJ, Chen WL, Lee-Chen GJ, Chen CM.
    • HTRA2 variations in Taiwanese Parkinson's disease.
      J Neural Transm. 2014; 121(5):491-8.
      Chen CM, Wu CH, Hsieh CH, Lin CH, Chen IC, Chen YC, Lee LC, Lee CM, Tseng YC, Lee-Chen GJ, Wu YR*.
    • Sex dimorphism of cortical water diffusion in normal aging measured by magnetic resonance imaging.
      Front Aging Neurosci. 2013;5:71.
      Ng SH, Hsu WC, Wai YY, Lee JD, Chan HL, Chen YL, Fung HC, Wu YR, Tsai ML, Wang JJ.
    • The experiences of taiwanese older individuals at different stages of Parkinson disease.
      J Neurosci Nurs. 2013;45(6):370-7.
      Liao YC, Wu YR, Tsao LI, Lin HR.
    • Internal Ribosome Entry Segment Activity of ATXN8 Opposite Strand RNA.
      PLoS One. 2013;8(9):e73885.
      Chen IC, Lin HY, Hsiao YC, Chen CM, Wu YR, Shiau HC, Shen YF, Huang KS, Su MT, Hsieh-Li HM, Lee-Chen GJ.
    • SLC1A2 Variant Is Associated with Essential Tremor in Taiwanese Population.
      PLoS One.2013;8(8):e71919.
      Yu SW, Chen CM, Chen YC, Chang CW, Chang HS, Lyu RK, Ro LS, Wu YR*.
    • Genetic variations of GAK in two Chinese Parkinson's disease populations: a case-control study.
      PLoS One. 2013 Jun 24;8(6):e67506.
      Tseng WE, Chen CM, Chen YC, Yi Z, Tan EK, Wu YR*.
    • Identification of a novel risk variant in the FUS gene in essential tremor.
      Neurology. 2013 Aug 6;81(6):541-544.
      Wu YR, Foo JN, Tan LC, Chen CM, Prakash KM, Chen YC, Bei JX, Au WL, Chang CW, Wong TY, Liu JJ, Zhao Y, Tan EK.
    • Long-term follow-up of spinal and bulbar muscular atrophy in Taiwan.
      J Formos Med Assoc. 2013 Jun;112(6):326-31.
      Fu SC, Kuo HC, Chu CC, Wu YR, Ro LS, Liu CS, Huang CC.
    • Association between PARK16 and Parkinson's disease in the Han Chinese population: a meta-analysis.
      Neurobiol Aging. 2013 Oct;34(10):2442.e5-9.
      Chang KH, Chen CM, Chen YC, Lyu RK, Chang HS, Ro LS, Lee-Chen GJ, Wu YR*.
    • Olfactory impairment and pathology in neurodegenerative disorders with brain iron accumulation.
      Acta Neuropathol. 2013 2013 Jul;126(1):151-3.
      Dziewulska D, Doi H, Fasano A, Erro R, Fatehi F, Fekete R, Gatto EM, Pablos EG, Lehn A, Miyajima H, Piperno A, Pellechia MT, Wu YR, Yoshida K, Zarruk JG, Jingli S, Schrag A, McNeill A.
    • Association between GRN rs5848 polymorphism and Parkinson's disease in Taiwanese population.
      PLoS One. 2013;8(1):e54448.
      Chang KH, Chen CM, Chen YC, Hsiao YC, Huang CC, Kuo HC, Hsu HC, Lee-Chen GJ, Wu YR*.
    • Aqueous Extract of Paeonia lactiflora and Paeoniflorin as Aggregation Reducers Targeting Chaperones in Cell Models of Spinocerebellar Ataxia 3.
      Evid Based Complement Alternat Med. 2013:471659.
      Chang KH, Chen WL, Lee LC, Lin CH, Kung PJ, Lin TH, Wu YC, Wu YR, Chen YC, Lee-Chen GJ, Chen CM.
    • Analyses of haptoglobin level in the cerebrospinal fluid and serum of patients with neuromyelitis optica and multiple sclerosis.
      Clin Chim Acta. 2013;417:26-30.
      Chang KH, Tseng MY, Ro LS, Lyu RK, Tai YH, Chang HS, Wu YR, Huang CC, Hsu WC, Kuo HC, Chu CC, Chen CM.
    • A comparison of benign and inflammatory manifestations of Tolosa-Hunt syndrome.
      Cephalalgia. 2013; Jul;33(10):842-52.
      Hung CH, Chang KH, Wu YM, Chen YL, Lyu RK, Chang HS, Wu YR, Chen CM, Huang CC, Chu CC, Liao MF, Wai YY, Hsu SP, Ro LS.
    • Genetic analysis of NFE2L2 promoter variation in Taiwanese Parkinson's disease.
      Parkinsonism Relat Disord 2013 Feb;19(2):247-50.
      Chen YC, Wu YR, Wu YC, Lee-Chen GJ, Chen CM.
    • Downregulation of genes involved in metabolism and oxidative stress in the peripheral leukocytes of Huntington's disease patients.
      PLoS One. 2012;7(9):e46492.
      Chang KH, Chen YC, Wu YR, Lee WF, Chen CM.
    • Protein kinase Cη polymorphism and the susceptibilities to intracerebral hemorrhage in the Taiwan population.
      Neurosci Lett. 2012 Oct 24;528(2).
      Chen YC, Chen P, Wu YR, Shie SS, Chen ST, Lee-Chen GJ, Chen CM.
    • Distinct features between longitudinally extensive transverse myelitis presenting with and without anti-Aquaporin 4 antibodies.
      Mult Scler. 2012 Jul 31. Mar;19(3):299-307.
      Chang KH, Lyu RK, Chen CM, Wu YR, Chang HS, Huang CC, Kuo HC, Chu CC, Hsu WC, Ro LS.
    • LRRK2 A419V Is Not Associated with Parkinson's Disease in Different Chinese Populations.
      PLoS One. 2012;7(7):e36123.
      Wu YR, Tan LC, Fu X, Chen CM, Au WL, Chen L, Chen YC, Prakash KM, Zheng Y, Lee-Chen GJ, Zhao Y, Zeng JS, Tan EK, Pei Z.
    • Effect of statin treatment on adrenomyeloneuropathy with cerebral inflammation: A revisit.
      Clin Neurol Neurosurg. 2013 May;115(5):624-7.
      Shih CC, Wu YR, Lee-Chen GJ, Chao CY.
    • ATXN8 -62 G/A promoter polymorphism and risk of Taiwanese Parkinson's disease.
      Eur J Neurol. 2012 Nov;19(11):1462-9.
      Chen IC, Wu YR(co- first author), Yang SJ, Kao SH, Chen YC, Chang KH, Lee CM, Lee-Chen GJ, Chen CM.
    • Genetic analysis of HLA-DRA region variation in Taiwanese Parkinson's disease.
      Parkinsonism Relat Disord. 2012 18:391-3.
      Chiang HL, Lee-Chen GJ, Chen CM, Chen YC, Lee CM, Liao MH, Wu YR*.
    • Identification of gene networks and pathways associated with guillain-barre syndrome.
      PLoS One. 2012;7(1):e29506.
      Chang KH, Chuang TJ, Lyu RK, Ro LS, Wu YR, Chang HS, Huang CC, Kuo HC, Hsu WC, Chu CC, Chen CM.
    • LINGO-2 polymorphism and risk of Parkinson's disease in Taiwan.
      Parkinsonism Relat Disord. 201 2012 Jun;18(5):609-11.
      Su FC, Chen CM, Chen YC, Wu YR*.
    • Are there ethnic differences in Impulsive/Compulsive behaviors in Parkinson's disease?
      Eur J Neurol 2012 19:494-500.
      Chiang HL, Huang YS, Chen ST, Wu YR*.