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醫療團隊

專業的醫護人員，提供最佳的醫療服務

醫師介紹

  •

張雅婷醫師

神經行為、神經醫學、頭痛治療、失智症治療、醫學影像學、退化型失智症、血管型失智症、頭痛、偏頭痛、張力型頭痛、睡眠障礙
  • 國語,英語,閩南語
  • 副教授
醫師網路掛號
直接點選進入醫師網路掛號畫面
醫師資歷
  • 現職
    • 高雄長庚醫院 神經科部 一般神經科 主治醫師
  • 學歷
    • 高雄中山大學 理學院 生物科學系 博士學位 2016.06
    • 高雄醫學大學 醫學系 學士學位 2006.06
  • 經歷
    • 高雄長庚神經科住院醫師
  • 論文及期刊發表
    • Chang YT, Lu CH. The role of oxidative stress, inflammatory and autonomic reflex in acute and convalescent stage of stroke (博士論文). 2016.

    • Chang YT, Kazui H, Ikeda M, Huang CW, Huang SH, Hsu SW, Chang WN, Chang CC. Genetic Interaction of APOE and FGF1 is Associated with Memory Impairment and Hippocampal Atrophy in Alzheimer’s Disease. Aging and Disease. 2019 Jun 1;10(3):510-519.

    • Chang YT, Mori E, Suzuki M, Ikeda M, Huang CW, Chang WN, Lee JJ, Chang CC. APOE-MS4A genetic interactions are associated with executive dysfunction and network abnormality in clinically mild Alzheimer's disease. NeuroImage: Clinical. 2019;21:101621.

    • Chang YT, Huang CW, Huang SH, Hsu SW, Chang WN, Lee JJ, Chang CC. Genetic interaction is associated with lower metabolic connectivity and memory impairment in clinically mild Alzheimer's disease. Genes Brain Behav. 2019 Jun;18(5):e12490.

    • Chen WC, Chang YT, Chen SF, Lin WC, Su YY, Luo SD. The symptom burden of autonomic dysfunction is positively associated with chronic rhinosinusitis status. Rhinology. 2018 Sep 1;56(3):227-233.

    • Hung CW, Lin WC, Chang WN, Su TM, Kung CT, Tsai NW, Wang HC, Huang CC, Cheng BC, Su YJ, Chang YT, Su CM, Hsiao SY, Lu CH. Risk factors and outcomes of cerebrospinal fluid overdrainage in HIV-negative patients with cryptococcal meningitis after the ventriculoperitoneal shunting procedure. J Microbiol Immunol Infect. 2018 Aug;51(4):545-551.

    • Su YJ, Tsai NW, Kung CT, Wang HC, Lin WC, Huang CC, Chang YT, Su CM, Chiang YF, Cheng BC, Lin YJ4, Lu CH. Investigation of MicroRNA in Mitochondrial Apoptotic Pathway in Systemic Lupus Erythematosus. Biomed Res Int. 2018 Jul 10;2018:9026357.

    • Chang YT, Huang CW, Chang WN, Lee JJ, Chang CC. Altered Functional Network Affects Amyloid and Structural Covariance in Alzheimer’s Disease. BioMed Research International. 2018 Dec 2;2018:8565620

    • Chang HI, Chang YT, Tsai SJ, Huang CW, Hsu SW, Liu ME, Chang WN, Lien CY, Huang SH, Lee CC, Chang CC. MAOA-VNTR Genotype Effects on Ventral Striatum-Hippocampus Network in Alzheimer's Disease: Analysis Using Structural Covariance Network and Correlation with Neurobehavior Performance. Mol Neurobiol. 2018 Oct 18.

    • Hsiao HT, Lee JJ, Chen HH, Wu MK, Huang CW, Chang YT, Lien CY, Wang JJ, Chang HI, Chang CC. Adequacy of nutrition and body weight in patients with early stage dementia: The cognition and aging study. Clin Nutr. 2018 Sep 22. pii: S0261-5614(18)32455-5. doi: 10.1016/j.clnu.2018.09.017.

    • Hung CW, Lin WC, Chang WN, Su TM, Kung CT, Tsai NW, Wang HC, Huang CC, Cheng BC, Su YJ, Chang YT, Su CM, Hsiao SY, Lu CH. Risk factors and outcomes of cerebrospinal fluid overdrainage in HIV-negative patients with cryptococcal meningitis after the ventriculoperitoneal shunting procedure. J Microbiol Immunol Infect. 2018 Aug; 51 (4): 545-551.

    • Lai YR, Lin YJ, Shih FY, Wang HC, Tsai NW, Kung CT, Lin WC, Cheng BC, Su YJ, Chang YT, Su CM, Hsiao SY, Huang CC, Lu CH. Effect of Baroreceptor Sensitivity on Outcomes in Patients with Acute Spontaneous Intracerebral Hemorrhage. World Neurosurg. 2018 Jan; 109.

    • Lee JJ, Chang WN, Hsu JL, Huang CW, Chang YT, Hsu SW, Huang SH, Lee CC, Lien CY, Chang CC. Diffusion kurtosis imaging as a neuroimaging biomarker in patients with carbon monoxide intoxication. Neurotoxicology. 2018 Jul 11; 68: 38-46.

    • Chang CC, Chang YT, Huang CW, Tsai SJ, Hsu SW, Huang SH, Lee CC, Chang WN, Lui CC, Lien CY. Associations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer's disease. Alzheimers Res Ther. 2018 Feb 8; 10 (1):17.

    • Huang CW, Hsu SW, Chang YT, Huang SH, Huang YC, Lee CC, Chang WN, Lui CC, Chen NC, Chang CC. Cerebral Perfusion Insufficiency and Relationships with Cognitive Deficits in Alzheimer's Disease: A Multiparametric Neuroimaging Study. Sci Rep. 2018 Jan 24; 8 (1): 1541

    • Chang CC, Tsai SJ, Chen NC, Huang CW, Hsu SW, Chang YT, Liu ME, Chang WN, Tsai WC, Lee CC. Catechol-O-Methyltransferase Val158Met Polymorphism on Striatum Structural Covariance Networks in Alzheimer's Disease. Mol Neurobiol. 2018 Jun; 55 (6): 4637-4649.

    • Chang YT, Lu CH, Wu ML, Hsu SW, Huang CW, Chang WN, Lien CY, Lee JJ, Chang CC. Salience Network and Depressive Severities in Parkinson’s Disease with Mild Cognitive Impairment: A Structural Covariance Network Analysis. Frontiers in Aging Neuroscience. 2018 Jan 10; 9: 417.

    • Chen SF, Liu MH, Chen NC, Horng HD, Tsao WL, Chang CC, Chang YT. Educational effect on Ascertain Dementia 8-item Informant Questionnaire to Detect Dementia in the Taiwanese population. Int Psychogeriatr. 2017 Dec 10:1-9

    • Chen CT, Chang CC, Chang WN, Tsai NW, Huang CC, Chang YT, Wang HC, Kung CT, Su YJ, Lin WC, Cheng BC, Su CM, Hsiao SY, Hsu CW, Lu CH (2017, Sep). Neuropsychiatric symptoms in Alzheimer's disease: associations with caregiver burden and treatment outcomes. QJM-an international journal of medicine. 2017 110 (9):565-570.

    • Fang YN, Tong MS, Sung PH, Chen YL, Chen CH, Tsai NW, Huang CJ, Chang YT, Chen SF, Chang WN, Lu CH, Yip HK (2017, Jun). Higher neutrophil counts and neutrophil-to-lymphocyte ratio predict prognostic outcomes in patients after non-atrial fibrillation-caused ischemic stroke. Biomedical Journal. 2017 40 (3):154-162.

    • Chang YT, Hsu SW, Tsai SJ, Chang YT, Huang CW, Liu ME, Chen NC, Chang WN, Hsu JL, Lee CC, Chang CC (2017, Jan). Genetic effect of MTHFR C677T polymorphism on the structural covariance network and white-matter integrity in Alzheimer's disease. Human Brain Mapping. 2017 38 (6):3039-3051.

    • Huang CW, Hsu SW, Tsai SJ, Chen NC, Liu ME, Lee CC, Huang SH, Chang WN, Chang YT, Tsai WC, Chang CC (2017, Jan). Genetic effect of interleukin-1 beta (C-511T) polymorphism on the structural covariance network and white matter integrity in Alzheimer's disease. Journal of Neuroinflammation, 2017 14(1):12.

    • Chang YT, Lin HC, Chang WN, Tsai NW, Huang CC, Wang HC, Kung CT, Su YJ, Lin WC, Cheng BC, Su CM, Chen TY, Chiang YF, Lu CH (2017, Jan).Impact of inflammation and oxidative stress on carotid intima-media thickness in obstructive sleep apnea patients without metabolic syndrome. J Sleep Res. 2017 Apr; 26 (2)

    • Kung CT, Su CM, Chen CT, Cheng HH, Chang MW, Hung CW, Hung SC, Chang WN, Tsai NW, Wang HC, Su YJ, Huang CC, Lin WC, Cheng BC, Chang YT, Lu CH. Circulating endothelial progenitor cells may predict outcomes in adult patients with severe sepsis in the emergency department. Clin Chim Acta. 2016 Apr 1;455:1-6.

    • Su CM, Cheng HH, Hung CW, Hsiao SY, Tsai NW, Chang WN, Wang HC, Lin WC, Cheng BC, Su YJ, Chang YT, Kung CT, Lu CH. The value of serial serum cell adhesion molecules in predicting acute kidney injury after severe sepsis in adults. Clin Chim Acta. 2016 Jun 1;457:86-91.

    • Lin PH, Chen HH, Chen NC, Chang WN, Huang CW, Chang YT, Hsu SW, Hsu CW, Chang CC (2016, Aug). Anatomical Correlates of Non-Verbal Perception in Dementia Patients. Frontiers in Aging Neuroscience. 2016 8:207

    • Chen NC, Chuang YC, Huang CW, Lui CC, Lee CC, Hsu SW, Lin PH, Lu YT, Chang YT, Hsu CW, Chang CC (2016, Jun). Interictal serum brain-derived neurotrophic factor level reflects white matter integrity, epilepsy severity, and cognitive dysfunction in chronic temporal lobe epilepsy. Epilepsy Behav., 59:147-54.

    • Chang CC*, Hsu JL, Chang WN, Huang SH, Huang CW, Chang YT, Chen NC, Lui CC, Lee CC, Hsu SW. (2016, Mar). Metabolic Covariant Network in relation to Nigrostriatal Degeneration in Carbon Monoxide Intoxication-related Parkinsonism. Frontiers in Neuroscience. 2016 10:187.

    • Chang YT, Huang CW, Chen NC, Lin KJ, Huang SH, Chang WN, Hsu CW, Chen HH, Chang CC. Hippocampal Amyloid Burden with Downstream Fusiform Gyrus Atrophy Correlate with Face Matching Task Scores in Early Stage Alzheimer’s Disease. Front Aging Neurosci. 2016; 8: 145

    • Chang YT, Huang CW, Chen NC, Lin KJ, Huang SH, Chang YH, Hsu SW, Chang WN, Lui CC, Hsu CW, Chang CC. Prefrontal Lobe Brain Reserve Capacity with Resistance to Higher Global Amyloid Load and White Matter Hyperintensity Burden in Mild Stage Alzheimer's Disease. PLoS One. 2016 Feb 12;11(2):e0149056.

    • Lu YT, Chang WN, Chang CC, Lu CH, Chen NC, Huang CW, Lin WC, Chang YT. Insula Volume and Salience Network Are Associated with Memory Decline in Parkinson Disease: Complementary Analyses of Voxel-Based Morphometry versus Volume of Interest. Parkinsons Dis. 2016;2016:2939528.

    • Wang HC, Lin YJ, Shih FY, Chang HW, Su YJ, Cheng BC, Su CM, Tsai NW, Chang YT, Kwan AL, Lu CH. The Role of Serial Oxidative Stress Levels in Acute Traumatic Brain Injury and as Predictors of Outcome. World Neurosurg. 2016 Mar; 87:463-70.

    • Chang YT, Chang WN, Tsai NW, Cheng KY, Huang CC, Kung CT, Su YJ, Lin WC, Cheng BC, Su CM, Chiang YF, Lu CH. Clinical Features Associated with Frozen Shoulder Syndrome in Parkinson’s Disease. Parkinson’s Disease. 2015; doi: 10.1155/2015/232958.

    • Chang YT, Chang WN, Tsai NW, Huang CC, Wang HC, Kung CT, Su YJ, Lin WC, Chang HW, Cheng BC, Su CM, Chiang YF, Lu CH. Cerebral Blood Flow Links Autonomic Function in Symptomatic Internal Carotid Artery Occlusion Survivors. Journal of the neurological sciences. 2015.

    • Chang YT, Huang CW, Chang YH, Chen NC, Lin KJ, Yan TC, Chang WN, SF, Lui CC, Lin PH, Chang CC. Amyloid burden in the hippocampus and default mode network: relationships with gray matter volume and cognitive performance in mild stage Alzheimer's disease. Medicine. 2015. April; 94:16.

    • Chen NC, Huang CW, Huang SH, Chang WN, Chang YT, Lui CC, Lin PH, Lee CC, Chang YH, Chang CC. Cognitive severity-specific neuronal degenerative network in charcoal burning suicide-related carbon monoxide intoxication: a multimodality neuroimaging study in Taiwan. Medicine. 2015 May;94(19):e783.

    • Wu MK, Lu YT, Huang CW, Lin PH, Chen NC, Lui CC, Chang WN, Lee CC, Chang YT, Chen SF, Chang CC. Clinical Significance of Cerebrovascular Biomarkers and White Matter Tract Integrity in Alzheimer Disease: Clinical correlations With Neurobehavioral Data in Cross-Sectional and After 18 Months Follow-ups. Medicine. 2015 Jul;94(28):e1192.

    • Chang YT, Lu CH, Chuang MJ, Huang CR, Chuang YC, Tsai NW, Chen SF, Chang CC, Chang WN. Supratentorial deep-seated bacterial brain abscess in adults: clinical characteristics and therapeutic outcomes. Acta Neurol Taiwan. 2010 Sep;19(3):178-83.

    • Chang CC, Lin PH, Chang YT, Chen NC, Huang CW, Lui CC, Huang SH, Chang YH, Lee CC, Lai WA. The Impact of Admission Diagnosis on Recurrent or Frequent Hospitalizations in 3 Dementia Subtypes: A Hospital-Based Cohort in Taiwan with 4 Years Longitudinal Follow-Ups. Medicine. 2015 Nov;94(46)

    • Huang CW, Tsai MH, Chen NC, Chen WH, Lu YT, Lui CC, Chang YT, Chang WN, Chang AY, Chang CC. Clinical significance of circulating vascular cell adhesion molecule-1 to white matter disintegrity in Alzheimer's dementia. Thromb Haemost. 2015 Nov 25;114(6):1230-40.

    • Kung CT, Su CM, Chang HW, Cheng HH, Hsiao SY, Tsai TC, Chang WN, Tsai NW, Wang HC, Su YJ, Huang CC, Lin WC, Cheng BC, Chang YT, Chiang YF, Lu CH. Serum adhesion molecules as outcome predictors in adult severe sepsis patients requiring mechanical ventilation in the emergency department. Clin Biochem. 2014 Jul 3.

    • Chang YT, Chang WN, Tsai NW, Huang CC, Kung CT, Su YJ, Lin WC, Cheng BC, Su CM, Chiang YF, Lu CH. The roles of biomarkers of oxidative stress and antioxidant in Alzheimer's disease: a systematic review. Biomed Res Int. 2014; 2014:182303.

    • Tsai NW, Chang YT, Huang CR, Lin YJ, Lin WC, Cheng BC, Su CM, Chiang YF, Chen SF, Huang CC, Chang WN, Lu CH. Association between oxidative stress and outcome in different subtypes of acute ischemic stroke. Biomed Res Int. 2014; 2014:256879. Epub 2014 May 8.

    • Su CM, Cheng HH, Tsai TC, Hsiao SY, Tsai NW, Chang WN, Lin WC, Cheng BC, Su YJ, Chang YT, Chiang YF, Kung CT, Lu CH. Elevated serum vascular cell adhesion molecule-1 is associated with septic encephalopathy in adult community-onset severe sepsis patients. Biomed Res Int. 2014; 2014: 598762.

    • Su YJ, Cheng TT, Chen CJ, Chiu WC, Chang WN, Tsai NW, Kung CT, Lin WC, Huang CC, Chang YT, Su CM, Chiang YF, Cheng BC, Lu CH. The association among antioxidant enzymes, autoantibodies, and disease severity score in systemic lupus erythematosus: comparison of neuropsychiatric and nonneuropsychiatric groups. Biomed Res Int. 2014; 2014:137231. doi: 10.1155/2014/137231. Epub 2014 Apr 27.

    • Su YJ, Huang CR, Chang WN, Tsai NW, Kung CT, Lin WC, Huang CC, Su CM, Cheng BC, Chang YT*, Lu CH. The association between autoantibodies and peripheral neuropathy in lupus nephritis. Biomed Res Int. 2014; 2014: 24940.

    • Hsu CW, Su YJ, Chang WN, Tsai NW, Chiu WC, Cheng BC, Su CM, Huang CR, Chang YT*, Lu CH. The association between serological biomarkers and primary Sjogren's syndrome associated with peripheral polyneuropathy. Biomed Res Int. 2014; 2014: 902492.

    • Tsai NW, Lee LH, Huang CR, Chang WN, Chang YT, Su YJ, Chiang YF, Wang HC, Cheng BC, Lin WC, Kung CT, Su CM, Lin YJ, Lu CH. Statin therapy reduces oxidized low density lipoprotein level, a risk factor for stroke outcome. Crit Care. 2014 Jan 14; 18(1).

    • Huang TL, Hsu HC, Chen HC, Lin HC, Chien CY, Fang FM, Huang CC, Chang HW, Chang WN, Huang CR, Tsai NW, Kung CT, Wang HC, Lin WC, Cheng BC, Su YJ, Chang YT, Chang CR, Tan TY, Lu CH. Long-term effects on carotid intima-media thickness after radiotherapy in patients with nasopharyngeal carcinoma. Radiat Oncol. 2013 Nov 7;8(1):261.

    • 8. Su YJ, Cheng TT, Chen CJ, Chiu WC, Hsu CY, Chang WN, Tsai NW, Kung CT, Wang HC, Lin WC, Huang CC, Chang YT, Su CM, Chiang YF, Cheng BC, Lin YJ, Lu CH. The association among leukocyte apoptosis, autoantibodies and disease severity in systemic lupus erythematosus. J Transl Med. 2013 Oct 19; 11:261. doi: 10.1186/1479-5876-11-261.

    • Cheng KY, Lin WC, Chang WN, Lin TK, Tsai NW, Huang CC, Wang HC, Huang YC, Chang HW, Lin YJ, Lee LH, Cheng BC, Kung CT, Chang YT, Su CM, Chiang YF, Su YJ, Lu CH. Factors associated with fall-related fractures in Parkinson's disease. Parkinsonism Relat Disord. 2014 Jan; 20 (1):88-92.

    • Huang CW, Chang WN, Huang SH, Lui CC, Chen NC, Chang YT, Lee CC, Chang CC, Chang AY. Impact of homocysteine on cortical perfusion and cognitive decline in mild Alzheimer's dementia. Eur J Neurol. 2013 Aug;20(8):1191-7.

    • Chen NC, Chang CC, Lin KN, Huang CW, Chang WN, Chang YT, Chen C, Yeh YC, Wang PN. Patterns of executive dysfunction in amnestic mild cognitive impairment. Int Psychogeriatr. 2013 Jul; 25 (7):1181-9.

    • Chang YT, Chang CC, Lin HS, Huang CW, Chang WN, Lui CC, Lee CC, Lin YT, Chen CH, Chen NC. Montreal cognitive assessment in assessing clinical severity and white matter hyperintensity in Alzheimer's disease with normal control comparison. Acta Neurol Taiwan. 2012 Jun;21(2):64-73

    • Chang YT, Lu CH, Lui CC, Chang WN. Antibiotic-treated Streptococcus sanguinis intracranial mycotic aneurysm. Kaohsiung J Med Sci. 2012 Mar; 28 (3):178-81. Epub 2012 Jan 16

    • Chen SF, Chang YT*,Lu CH, Huang CR, Tsai NW, Chang CC, Huang CC, Chuang YC, Chang WN. Sweat output measurement of the post-ganglion sudomotor response by Q-Sweat test: a normative database of Chinese individuals. BMC Neurosci. 2012 Jun 8;13:62