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醫療團隊

專業的醫護人員，提供最佳的醫療服務

醫師介紹

  •

李志宏醫師

皮膚免疫學、皮膚生理學、乾癬、異位性皮膚炎
  • 國語,英語,閩南語
  • 教授
醫師網路掛號
直接點選進入醫師網路掛號畫面
醫師資歷
  • 現職
    • 高雄長庚紀念醫院皮膚部教授級主治醫師
    • 長庚大學醫學院兼任教授
    • 臺灣教育部部定教授
    • 臺灣皮膚科醫學會常務理事
    • 臺灣研究皮膚科學會秘書長
    • Dermatologica Sinica主編(SCI雜誌)
  • 學歷
    • 高雄醫學大學醫學博士
    • 高雄醫學院醫學士
  • 經歷
    • 高雄長庚紀念醫院皮膚部主任(2013~2020)
    • Dermatologica Sinica主編(SCI雜誌)(2018~)
    • 台灣皮膚科醫學會常務理事(2018~)
    • 台灣皮膚科醫學會理事(2015~)
    • 台灣研究皮膚科學會秘書長(2018~)
    • 台灣研究皮膚科學會常務理事(2012~2018)
    • 高雄醫學大學皮膚科部定副教授(2012-2013)
    • 高雄醫學大學皮膚科部定助理教授(2009-2012)
    • 高雄市立小港醫院皮膚科主任(2008-2013)
    • 美國NIH國家癌症中心客座學者(2004-2006)
    • 高雄醫學大學附設醫院主治醫師(2003-2013)
  • 學會與認證
    • 台灣皮膚科醫學會專科醫師
    • 台灣皮膚科醫學會常務理事
    • 台灣研究皮膚科學會秘書長
    • 台灣乾癬免疫學會理事
    • 台灣教育部部定教授
    • 台灣醫學教育學會會員
    • 美國研究皮膚科學會會員
  • 論文及期刊發表
    • CCL21 Induces mTOR-dependent MALAT1 expression, leading to cell migration in cutaneous T-cell lymphoma.
      In Vivo. 33(3):793-800, 2019.
      Hong CH, Lin SH, Lee CH*.
    • Identification of pyruvatekinase 2 as a possible crab allergen and analysis of allergenic proteins in crabs consumed in Taiwan.
      Food Chem. 15;289:413-418, 2019.
      Wu CC, Lee CH (equal contribution), Tyan YC, Huang ES, Yu WT, Yu HS.
    • MiR-146a-5p expression in peripheral CD14?monocytes from patients with psoriatic arthritis induces osteoclast activation, bone resorption, and correlates with clinical response.
      J Clin Med. 8(1). pii: E110, 2019.
      Lin SH, Ho JC, Li SC, Chen JF, Hsiao CC, Lee CH*.
    • Treatment with TNF-a inhibitor rectified M1 macrophage polarization from blood CD14+ monocytes in patients with psoriasis independent of STAT1 and IRF-1 activation.
      J Dermatol Sci, 91(3):276-284. 2018.
      Lin SH, Chuang HY, Ho JC, Lee CH*, Hsiao CC.
    • Early sign of microangiopathy in systemic sclerosis: the significance of cold stress test in dynamic laser Doppler flowmeter.
      Clin Hemorheol Microcir, doi: 10.3233/CH-180419.
      Yu S, Hu SCS, Yu HS, Chin YY, Cheng YC, Lee CH*.
    • Identification of pyruvate kinase as a novel allergen in whiteleg shrimp (Litopenaeus vannamei) by specific-IgE present in patients with shrimp allergy.
      Food Chem 258:359-365, 2018.
      Lee CH, Wu CC, Tyan YC, Yu WT, Huang ES, Yu HS.
    • Clinicopathological features and course of cutaneous protothecosis.
      J Eur Acad Dermatol Venereol. 32:1575-1583, 2019.
      Tseng HC, Chen CB, Ho JC, Cheng YW, Huang HW, Sun PL, Lee CH*.
    • Pathophysiology of arsenic-induced adverse health effects.
      Hong Kong J Dermatol Venereol 25, 171-177, 2017.
      Lee CH*.
    • Solanum incanum extract (SR-T100) induces melanoma cell apoptosis and inhibits established lung metastasis.
      Oncotarget, 8:103509-103517, 2017.
      Yu S, Sheu HM, Lee CH.*
    • Inflammatory and noninflammatory itch: implications in pathophysiology-directed treatments.
      Int J Mol Sci. 18(7). pii: E1485, 2017.
      Wong LS, Wu T, Lee CH*.
    • Chronic eczematous dermatitis in patients with neurodegenerative diseases may be an early marker of bullous pemphigoid.
      Med Hypotheses.103:86-89, 2017.
      Chou, P.S., Chou, T.C., Chang, C.H., Yu, S., Lee, C.H*.
    • Linear and whorled nevoid hypermelanosis versus incontinentia pigmenti: Pigmentary incontinence is not a differential histological feature.
      Dermatol Sin. 34:221-222, 2017
      Chih, P.L., Lee, C.H*.
    • Differential activation behavior of dermal dendritic cells underlies the strain-specific Th1 responses to single epicutaneous immunization.
      J Dermatol Sci. J Dermatol Sci. 84:248-257, 2016.
      Lee, C.H., Chen, J.S., Chiu, H.C., Hong, C.H., Liu, C.Y., Ta, Y.C., Wang, L.F*.
    • Treatment of pigmented basal cell carcinoma with 3?mm surgical margin in Asians.
      Biomed Res Int. 2016:7682917, 2016.
      Lin, S.H., Cheng, Y.W., Yang, Y.C., Ho, J.C, Lee, C.H*.
    • Presence of the Merkel cell polyomavirus in Merkel cell carcinoma combined with squamous cell carcinoma in a patient with chronic arsenism.
      Clin Exp Dermatol. 41:902-905, 2016.
      Chou, T.C., Tsai, K.B., Wu, C.Y., Hong, C.H., Lee, C.H*.
    • Role of mitochondria, ROS, and DNA damage in arsenic induced carcinogenesis.
      Front Biosci (Schol Ed). 8:312-20, 2016.
      Lee, C.H., Yu, H.S.
    • Benzopyrene, a major polyaromatic hydrocarbon in smoke fume, mobilizes Langerhans cells and polarizes Th2/17 responses in epicutaneous protein sensitization through the aryl hydrocarbon receptor.
      Int Immunopharmacol. 36:111-117, 2016.
      Hong, C.H., Lee, C.H., Yu, H.S., Huang, S.K.
    • Progression of idiopathic eruptive macular pigmentation in a girl from childhood to adolescence.
      Pediatr Dermatol. 33:e299-302, 2016.
      Tsai, W., Lan, J,, Lee, C.H*.
    • Cumulative arsenic exposure is associated with fungal infections: two cohort studies based on southwestern and northeastern basins in Taiwan.
      Enviorn Int, 96:173-179, 2016.
      Hsu, L.I., Cheng, Y.W., Chen, C.J., Wu, M.M., Hsu, K.H., Chiou, H.Y., Lee, C.H*.
    • Arsenite regulates prolongation of glycan residues of membrane glycoprotein: a pivotal study via wax physisorption kinetics and FTIR imaging.
      Int J Mol Sci. 17pii: E427, 2016.
      Lee, C.H., Hsu, C.Y., Huang, P.Y., Chen, C.I., Lee, Y.C., Yu, H.S.
    • Differential immunological effects of infrared irradiation and its associated heat in vivo.
      J Photochem Photobiol B. 155: 98–103, 2016.
      Lee, C.H., Hong, C.H., Liao, W.T., Yu, H.S.
    • An estimation of the incidence of tuberous sclerosis complex by a nationwide retrospective cohort study from 1997 to 2010.
      Brit J Dermatol. 174:1282-9, 2016.
      Hong, C.H., Tu, H.P., Lin, J.R., Lee, C.H*.
    • Bull's eye dermatoscopy pattern at Bacillus Calmettee-Guerin inoculation site correlates with systemic involvements in patients with Kawasaki disease.
      J Dermatol, 43:1044-50, 2016.
      Tseng, H.C., Ho, J.C., Kuo, M.H., Lo, M.H., Hsieh, K.S., Tsai, W.C., Kuo, H.O., Lee, C.H*.
    • Web-based learning system for developing and assessing clinical diagnostic skills for dermatology residency program.
      Educ Technol Soc. 19:194-206, 2016.
      Kuo, F.R., Chin, Y.Y., Lee, C.H., Chiu, Y.H., Hong, C.H., Lee, K.L., Ho, W.H., Lee, C.H*.
    • Effect of heme oxygenase-1 gene promoter polymorphism on cancer risk by histological subtype: A prospective study in arseniasis-endemic areas in Taiwan.
      Int J Cancer. 2016 Apr 15;138(8):1875-86.
      Wu MM*, Lee CH, Hsu LI, Cheng WF, Lee TC, Wang YH, Chiou HY, Chen CJ.
    • Immune regulation in pathophysiology and targeted therapy for itch in atopic dermatitis.
      Dermatologica Sinica Volume 34, Issue 1, March 2016, Pages 1–5.
      Chih-Hung Lee*.
    • Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature.
      Dermatologica Sinica Volume 34, Issue 1, March 2016, Pages 29–32.
      Hsin-Wei Huang, Lai-San Wong, Chih-Hung Lee.
    • No Significant Reduction of Circulating Endothelial-Derived and Platelet-Derived Microparticles in Patients with Psoriasis Successfully Treated with Anti-IL12/23
      BioMed Research International Volume 2016, Article ID 3242143, 6 pages
      Ji-Chen Ho, Chih-Hung Lee, and Shang-Hung Lin
    • Dermal dendritic cells, but not Langerhans cells, are critical in murine single epicutaneous sensitization.
      Exp Dermatol. 2015 Jan;24(1):67-9.
      Lee CH, Chen JS, Chiu HC, Hong CH, Liu CY, Ta YC, Clausen BE, Ho JC, Wang LF*.
    • IL-9 induces IL-8 production via STIM1 activation and ERK phosphorylation in epidermal keratinocytes: A plausible mechanism of IL-9R in atopic dermatitis.
      J Dermatol Sci. 2015 Jun;78(3):206-14.
      Hong CH, Chang KL, Wang HJ, Yu HS, Lee CH.
    • STAT3-dependent VEGF production from keratinocytes abrogates dendritic cell activation and migration by arsenic: a plausible regional mechanism of immunosuppression in arsenical cancers.
      Chem Biol Interact. 2015 Feb 5;227:96-103.
      Hong CH, Lee CH, Chen GS, Chang KL, Yu HS*.
    • Prurigo Nodularis Is Associated with Depression and Anxiety in Chronic Hemodialysis Patients
      臺灣腎臟醫學會雜誌29:2 2015.06[民104.06]頁94-101.
      Tseng, Han-chi ; Tsai, Wen-chien ; Ho, Ji-chen ; Lee, Chih-hung ; Chen, Chien-chin ; Lee, Yueh-ting ; Lin, Shang-hong ; Lee*, Chien-te.
    • Taiwanese Dermatological Association consensus for the management of atopic dermatitis.
      Dermatologica Sinica December 2015 Volume 33, Issue 4, Pages 220–230.
      Chia-Yu Chu, Chi-Hung Lee, I-Hsin Shih, Hsiu-Chin Chen, Po-Han Huang, Chin-Yi Yang, Wen-Jen Wang, Yi-Ju Chen, Hamm-Ming Sheu, Wei-Ming Wang,Woan-Ruoh Lee, Yuan-Hsin Lo. Yang-Shia Dai, Li-Fang Wang, Tsen-Fang Tsai, Chih-Hsun Yang.
    • Association between the synthetic vascular stent used for abdominal aortic aneurysm and generalized granuloma annulare.
      Dermatologica Sinica Volume 33, Issue 3, September 2015, Pages 160–162.
      Han-Chi Tseng, Chih-Hung Lee*.
    • Refractory urticaria in adult-onset Still's disease.
      Rheumatology International. July 2014, Volume 34, Issue 7, pp 1029-1030
      Han-Chi Tseng, Chih-Hung Lee
    • Betel chewing and arecoline affects eotaxin-1, asthma and lung function.
      PLoS One. Published: March 21, 2014‧DOI: 10.1371/journal.pone.0091889
      Tsu-Nai Wang, Ming-Shyan Huang, Meng-Chih Lin, Tsai-Hui Duh, Chih-Hung Lee, Chin-Chou Wang, Ping-Ho Chen, Shang-Lun Chiang, Chau-Chyun Sheu, Vincent Chin-Hung Chen, Chao-Chien Wu equal contributormail, Cleusa P. Ferri, Robert Stewart, Ying-Chin Ko
    • Female gender and acne disease are jointly and independently associated with the risk of major depression and suicide: A national population-based study
      BioMed Research InternationalVolume 2014 (2014), Article ID 504279, 7 pages
      Yi-Chien Yang, Hung-Pin Tu, Chien-Hui Hong, Wei-Chao Chang, Hung-Chun Fu, Ji-Chen Ho, Wei-Pin Chang, Hung-Yi Chuang, and Chih-Hung Lee
    • Primary cutaneous tuberculosis in an elderly man.
      Q J Med 2014; 107:1043–1044
      Tseng HC, Lee CH, Cheng YW
    • A polymorphism of ORAI1 rs7135617, is associated with susceptibility to rheumatoid arthritis.
      Mediators of InflammationVolume 2014 (2014), Article ID 834831, 5 pages
      Jeng-Hsien Yen, Che-Mai Chang, Yu-Wen Hsu, Chih-Hung Lee, Mei-Shin Wu, Daw-Yang Hwang, Ben-Kuen Chen, Hsien-Tzung Liao, Man-Tzu Marcie Wu, and Wei-Chiao Chang
    • Apoptosis Induced by 2-Aryl Benzothiazoles-Mediated Photodynamic Therapy in Melanomas via Mitochondrial Dysfunction.
      Chem Res Toxicol. 2014 Jul 21;27(7):1187-98. doi: 10.1021/tx500080w. Epub 2014 Jun 13.
      Chen YK, Senadi GC, Lee CH, Tsai YM, Chen YR, Hu WP, Chou YW, Kuo KK, Wang JJ.